75415-03-1

Basic information

• Product Name: 2-(1H-PYRAZOL-3-YL)PYRIDINE
• Synonyms: BUTTPARK 17\04-92;2-(1H-PYRAZOL-3-YL)PYRIDINE;3-(Pyridin-2-yl)-1H-pyrazol;2-(1H-pyrazol-5-yl)pyridine;Pyridine, 2-(1H-pyrazol-3-yl)-;2-(PYRAZOL-3-YL)-PYRIDINE;2-(3-Pyrazolyl)pyridine;2-(2H-pyrazol-3-yl)pyridine
• CAS NO: 75415-03-1
• Molecular Formula: C₈H₇N₃
• Molecular Weight: 145.16
• Product Categories: Heterocycle-Pyridine series
• Mol File: 75415-03-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 119-120°C
• Boiling Point: 362.2 °C at 760 mmHg
• Flash Point: 179.2 °C
• Appearance: /
• Density: 1.214 g/cm³
• Vapor Pressure: 4.1E-05mmHg at 25°C
• Refractive Index: 1.61
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 11.36±0.10(Predicted)
• CAS DataBase Reference: 2-(1H-PYRAZOL-3-YL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-PYRAZOL-3-YL)PYRIDINE(75415-03-1)
• EPA Substance Registry System: 2-(1H-PYRAZOL-3-YL)PYRIDINE(75415-03-1)

Safety Data

• Hazard Codes: Xi
• Statements: Xi:刺激性物质
• HazardClass: IRRITANT
• Hazardous Substances Data: 75415-03-1(Hazardous Substances Data)

Usage

General Description

2-(1H-Pyrazol-3-yl)pyridine, also known as 3-pyridin-2-yl-1H-pyrazole, is an organic compound with the molecular formula C10H8N4. It is a heterocyclic compound composed of a pyridine ring fused to a pyrazole ring. This chemical is commonly used in pharmaceutical research and drug development due to its potential biological activities and therapeutic properties. It has been studied for its potential as an inhibitor of certain enzymes and for its potential applications in the treatment of various diseases. Additionally, 2-(1H-Pyrazol-3-yl)pyridine may also be used as an intermediate in the synthesis of other organic compounds in the field of medicinal chemistry and pharmaceuticals.

InChI:InChI=1/C8H7N3/c1-2-5-9-7(3-1)8-4-6-10-11-8/h1-6H,(H,10,11)

Upstream product

• 66521-54-8 3-(dimethylamino)-1-(pyridine-2-yl)prop-2-en-1-one 
• 60325-13-5 (+)-(1-Phenylethyl)hydrazin 

Downstream Products

• 214898-33-6 2-diphenylphosphino-6-[3-(2'-pyridyl)pyrazol-1-yl]pyridine 
• 209547-52-4 1,3-bis((3-(pyridin-2-yl)-1H-pyrazol-1-yl)methyl)benzene 
• 264205-79-0 C₆H₄C₆H₄(CH₂C₃H₂N₂C₅H₄N)2 
• 635684-02-5 1,3,5-trimethyl-2,4,6-tris(3-{pyridin-2-yl}-pyrazol-1-yl-methyl)benzene 
• 546142-39-6 2-[1-(4-nitrophenyl)-1H-pyrazol-3-yl]pyridine 
• 917244-81-6 C₆H₃CH₃(CH₂C₃H₂N₂C₅H₄N)2 
• 192711-20-9 2-(4-nitro-1H-pyrazol-3-yl)pyridine 
• 1259931-01-5 (carbonyl)(hydrido)[2-(1H-pyrazol-3-yl)pyridine]bis(triphenylphosphane)ruthenium chloride 
• 1259931-07-1 (carbonyl)(hydrido)[5-(pyridin-2-yl)pyrazol-1-ido]bis(triphenylphosphane)ruthenium 
• 1228341-16-9 4-[2-(1H-pyrazol-3-yl)pyridyl-1-ylmethyl]benzonitrile 
• 162435-06-5 1-methyl-3-(pyridin-2-yl)-1H-pyrazole 

Relevant articles and documents

Asymmetric Catalysis, 77. - New Optically Active Pyrazole Derivatives for Enantioselective Catalysis

Starting from the amines 3-6 and the dipyrazolopyrazinedione 2, the optically active (pyrazolylmethyl)amines 11-14 have been synthesized.Furthermore, the preparation of the (+)-camphor-derived optically active pyrazole 17 is described.Pyrazoles 11-13 and 17 are introduced as chiral building blocks into the 2-(1-pyrazolyl)pyridines 30-33.The optically active compounds 23-25 are formed from 2-pyridine and 2,6-bispyridine, respectively, and (+)-3-(bromomethyl)pinane.The pyrazole derivatives 27-29 contain (+)-(1-phenylethyl)hydrazine as the optically active component.Key Words: Pyrazoles, optically active / Pyridines, 2--, 2,6-bis-, 2-(1-pyrazolyl)-