754190-39-1 Usage
Uses
Used in Pharmaceutical Research:
N-BENZYL-4,6-DIIODOPYRIMIDIN-5-AMINE is used as a key intermediate in the synthesis of novel drug compounds, particularly for the development of therapeutic agents targeting various diseases and conditions. Its unique structure, including the iodine atoms and benzyl group, allows for the creation of new chemical entities with potential medicinal properties.
Used in Organic Synthesis:
In the field of organic synthesis, N-BENZYL-4,6-DIIODOPYRIMIDIN-5-AMINE serves as a valuable building block for the construction of complex organic molecules. Its reactivity and functional groups enable the formation of a wide range of chemical products, contributing to the advancement of organic chemistry.
Used in Materials Science:
N-BENZYL-4,6-DIIODOPYRIMIDIN-5-AMINE may also have potential applications in materials science, where its unique properties could be leveraged to develop new materials with specific characteristics. The presence of iodine atoms and the benzyl group could influence the material's properties, such as stability, solubility, or reactivity.
Used as a Reagent in Chemical Reactions:
In addition to its applications in synthesis and research, N-BENZYL-4,6-DIIODOPYRIMIDIN-5-AMINE can be employed as a reagent in various chemical reactions. Its ability to participate in a range of reactions, such as substitution, addition, or condensation, makes it a versatile tool in the chemist's arsenal.
Check Digit Verification of cas no
The CAS Registry Mumber 754190-39-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,4,1,9 and 0 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 754190-39:
(8*7)+(7*5)+(6*4)+(5*1)+(4*9)+(3*0)+(2*3)+(1*9)=171
171 % 10 = 1
So 754190-39-1 is a valid CAS Registry Number.
754190-39-1Relevant academic research and scientific papers
Design, synthesis, and structure-activity relationship of 6-alkynylpyrimidines as potent adenosine kinase inhibitors
Gomtsyan, Arthur,Didomenico, Stanley,Lee, Chih-Hung,Matulenko, Mark A.,Kim, Ki,Kowaluk, Elizabeth A.,Wismer, Carol T.,Mikusa, Joe,Yu, Haixia,Kohlhaas, Kathy,Jarvis, Michael F.,Bhagwatt, Shripad S.
, p. 3639 - 3648 (2007/10/03)
Adenosine (ADO) is an extracellular signaling molecule within the central and peripheral nervous system. Its concentration is increased at sites of tissue injury and inflammation. One of the mechanisms by which antinociceptive and antiinflammatory effects of ADO can be enhanced consists of inhibition of adenosine kinase (AK), the primary metabolic enzyme for ADO. Novel nonnucleoside AK inhibitors based on 4-amino-6-alkynylpyrimidines were prepared, and the importance of the length of the linker at the 5-position for high affinity AK inhibition was demonstrated. Compounds with 2- and 3-atom linkers were the most potent AK inhibitors. Optimization of their physicochemical properties led to 31a and 37a that effectively reduced pain and inflammation in animal models.
