754201-28-0Relevant articles and documents
Nickel-Catalyzed Enantioselective Conjunctive Cross-Coupling of 9-BBN Borates
Chierchia, Matteo,Law, Chunyin,Morken, James P.
, p. 11870 - 11874 (2017)
Catalytic enantioselective conjunctive cross-coupling between 9-BBN borate complexes and aryl electrophiles can be accomplished with Ni salts in the presence of a chiral diamine ligand. The reactions furnish chiral 9-BBN derivatives in an enantioselective fashion and these are converted to chiral alcohols and amines, or engaged in other stereospecific C?C bond forming reactions.
Synthesis of (3R,5S)-5-hydroxy-de-O-methyllasiodiplodin: A facile and stereoselective approach
Bujaranipalli, Sheshurao,Das, Saibal
supporting information, p. 3747 - 3749 (2015/06/08)
A concise and facile synthesis of (3R,5S)-5-hydroxy-de-O-methyllasiodiplodin has been demonstrated in 12 steps starting from methylacetoacetate and (±)propylene oxide. The key reactions involved are Jacobsen's hydrolytic kinetic resolution, Sharpless asymmetric epoxidation, Mitsunobu, and ring closing metathesis reaction for the construction of macrolactone with two chiral substitutions on it.
Modular asymmetric synthesis of pochonin C
Barluenga, Sofia,Lopez, Pilar,Moulin, Emilie,Winssinger, Nicolas
, p. 3467 - 3470 (2007/10/03)
Back to its origins: Pochonin C was synthesized in 11 steps from the four fragments shown in the scheme. This asymmetric synthesis and the conversion of pochonin C into radicicol defines the configuration at the center bearing the chlorine atom as S. lpc
