754224-71-0

Basic information

• Product Name: (1R,4S,5R,6S)-1-C-(acetoxymethyl)-4,5,6-tri(benzyloxy)cyclohex-2-en-1-ol
• CAS NO: 754224-71-0
• Molecular Weight: 488.58
• Mol File: 754224-71-0.mol

Chemical Properties

• CAS DataBase Reference: (1R,4S,5R,6S)-1-C-(acetoxymethyl)-4,5,6-tri(benzyloxy)cyclohex-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,4S,5R,6S)-1-C-(acetoxymethyl)-4,5,6-tri(benzyloxy)cyclohex-2-en-1-ol(754224-71-0)
• EPA Substance Registry System: (1R,4S,5R,6S)-1-C-(acetoxymethyl)-4,5,6-tri(benzyloxy)cyclohex-2-en-1-ol(754224-71-0)

Safety Data

• Hazardous Substances Data: 754224-71-0(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 85798-11-4 (4S,5R,6S)-4,5,6-tris-benzyloxycyclohex-2-en-1-one 
• 88023-78-3 para-methoxybenzyl chloride 

Downstream Products

• 754224-47-0 Phthalic acid 1-((1R,4S,5R,6S)-1-acetoxy-4,5,6-tris-benzyloxy-cyclohex-2-enylmethyl) ester 2-((2S,3R,4S,5R,6R)-3-azido-4,5-bis-benzyloxy-6-methoxy-tetrahydro-pyran-2-ylmethyl) ester 
• 148347-74-4 (1R,4S,5R,6S)-4,5,6-tri(benzyloxy)-1-C-(hydroxymethyl)cyclohex-2-en-1-ol 

Relevant articles and documents

An investigation into the synthesis of some molecules related to methyl acarviosin

Methyl acarviosin is an impressive inhibitor of some glycoside hydrolases that process substrates containing α-D-glucosidic linkages. In an attempt to provide putative inhibitors for enzymes that process β-D-glucosidic linkages, we report an improved synthesis of a hydroxylated 'methyl β-acarviosin' and our efforts towards various deoxygenated versions of methyl β-acarviosin. As well, the synthesis of a 1,3-linked variant of methyl β-acarviosin is reported, together with an unsuccessful 'tether' approach to construct the crucial nitrogen linkage in the acarviosins.