754226-38-5

Basic information

• Product Name: 2-(3,4-Difluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: 3,4-Difluoro-5-methoxyphenylboronic acid, pinacol ester;2-(3,4-Difluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 754226-38-5
• Molecular Formula: C13H17BF2O3
• Molecular Weight: 270.0800864
• Mol File: 754226-38-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 2-(3,4-Difluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-Difluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(754226-38-5)
• EPA Substance Registry System: 2-(3,4-Difluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(754226-38-5)

Safety Data

• Hazardous Substances Data: 754226-38-5(Hazardous Substances Data)

Usage

General Description

2-(3,4-Difluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a chemical compound that belongs to the class of boron-containing compounds. It is a boronic acid derivative and is commonly used in organic synthesis as a building block for various pharmaceuticals, agrochemicals, and materials. 2-(3,4-Difluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is known for its high stability and reactivity, making it a valuable tool in the field of organic chemistry. It is often used in cross-coupling reactions and as a precursor in the synthesis of heterocyclic compounds. Additionally, it has potential applications in medicinal chemistry and drug discovery due to its ability to modulate biological processes.

Upstream product

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Relevant articles and documents

NOVEL HETEROCYCLIC COMPOUNDS

The invention provides novel heterocyclic compounds having thegeneral formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R4, m, n, and p are as described herein. Formula (I). Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

C-H Functionalization at Sterically Congested Positions by the Platinum-Catalyzed Borylation of Arenes

Despite significant progress in the area of C-H bond functionalization of arenes, no general method has been reported for the functionalization of C-H bonds at the sterically encumbered positions of simple arenes, such as mesitylene. Herein, we report the development of the first platinum-based catalyst for C-H borylation of arenes and heteroarenes. Notably, this method exhibited high tolerance toward steric hindrance and provided rapid access to a series of 2,6-disubstituted phenylboronic esters, valuable building blocks for further elaborations.