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CAS

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75453-27-9

diethyl 4-oxo-6-phenoxy-10-propyl-4H-pyrano<3,2-g>quilnoline-2,8-dicarboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 75453-27-9 Structure

  • Basic information

    1. Product Name: diethyl 4-oxo-6-phenoxy-10-propyl-4H-pyrano<3,2-g>quilnoline-2,8-dicarboxylate
    2. Synonyms: diethyl 4-oxo-6-phenoxy-10-propyl-4H-pyrano<3,2-g>quilnoline-2,8-dicarboxylate
    3. CAS NO:75453-27-9
    4. Molecular Formula:
    5. Molecular Weight: 475.498
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 75453-27-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: diethyl 4-oxo-6-phenoxy-10-propyl-4H-pyrano<3,2-g>quilnoline-2,8-dicarboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: diethyl 4-oxo-6-phenoxy-10-propyl-4H-pyrano<3,2-g>quilnoline-2,8-dicarboxylate(75453-27-9)
    11. EPA Substance Registry System: diethyl 4-oxo-6-phenoxy-10-propyl-4H-pyrano<3,2-g>quilnoline-2,8-dicarboxylate(75453-27-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 75453-27-9(Hazardous Substances Data)

75453-27-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 75453-27-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,5 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 75453-27:
(7*7)+(6*5)+(5*4)+(4*5)+(3*3)+(2*2)+(1*7)=139
139 % 10 = 9
So 75453-27-9 is a valid CAS Registry Number.

75453-27-9Relevant articles and documents

New Antiallergic Pyranoquinoline-2,8-dicarboxylic Acids with Potential for the Topical Treatment of Asthma

Cairns, Hugh,Cox, David,Gould, Ken J.,Ingall, Anthony H.,Suschitzky, John L.

, p. 1832 - 1842 (2007/10/02)

A nimber of antiallergic pyranoquinolinedicarboxylic acid derivatives with potential for the topical treatment of asthma have been synthesized.All the compounds have been evaluated against rat passive cutaneous anaphylaxis and in a dog hypotension screen.This is the first detailed description of the application of the latter screen for the identification of antiallergic agents.Two compounds, disodium 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyranoquinoline-2,8-dicarboxylate (86) and disodium 6-(methylamino)-4-oxo-10-propyl-4H-pyranoquinoline-2,8-dicarboxylate (72), were selected and further evaluated for their ability to induce phosphorylation of a 78000 molecular weight protein associated with the rat peritoneal mast cell.Their ability to inhibit histamine release from these cells and from a mucosal mast cell preparation has also been evaluated.These compounds, nedocromil sodium (TILADE 86) and minocromil (the free acid of 72), are at present undergoing therapeutic evaluation.The rationale for the screening procedure and the relevance of the second carboxylic acid function of these dibasic acids to receptor binding are discussed.

Pyranoquinolinones and analogs thereof

-

, (2008/06/13)

There are described compounds of formula I, STR1 in which an adjacent pair of R5, R6, R7 and R8 form a chain --CZC(G1)=(G2)--Z--, R4, R9 and the remainder of R5/

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