75458-46-7Relevant academic research and scientific papers
Zirconium-catalyzed ethylmagnesiation of imines - Scope and mechanism
Gandon, Vincent,Bertus, Philippe,Szymoniak, Jan
, p. 3677 - 3681 (2007/10/03)
The title reaction has been developed for a series of aldimines and ketimines. Most notably, ketimines - which are totally inert towards alkyl Grignard reagents in the absence of the zirconium catalyst - react smoothly when 10 mol % of Cp2ZrCl2 is added. The mechanism of the reaction has been studied. The intermediate azazirconacycle proved to react by two competing pathways involving mono- and dimagnesiated final products before hydrolysis.
Stereospecific Synthesis of N-Substituted cis-2-Aryl-3-alkylaziridines
Kimpe, Norbert De,Verhe, Roland,Buyck, Laurent De,Schamp, Niceas
, p. 5319 - 5325 (2007/10/02)
A convenient stereospecific synthesis of N-substituted cis-2-aryl-3-alkylaziridines is reported, by reaction of N-alkyl or N-aryl α,α-dichloroalkyl aryl ketimines with lithium aluminum hydride in ethereal medium.The mechanism involves the addition of hydr
