6852-58-0

Basic information

• Product Name: 2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE
• Synonyms: N-tert-Butylbenzylimine;N-tert-Butylbenzylimine 97%;2-Methyl-N-(phenylmethylene)-2-propylamine ,98%;N-Benzylidene-1,1-dimethylethanamine;N-Benzylidene-2-methyl-2-propanamine;N-Benzylidene-2-methylpropane-2-amine;N-Benzylidene-N-tert-b;N-tert-butyl-1-phenylmethanimine
• CAS NO: 6852-58-0
• Molecular Formula: C₁₁H₁₅N
• Molecular Weight: 161.24
• Product Categories: Imines/Amidines;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 6852-58-0.mol
• Article Data: 146

Chemical Properties

• Melting Point: -30
• Boiling Point: 209 °C(lit.)
• Flash Point: 173 °F
• Appearance: /
• Density: 0.906 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.093mmHg at 25°C
• Refractive Index: n20/D 1.52(lit.)
• PKA: 6.31±0.50(Predicted)
• CAS DataBase Reference: 2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE(6852-58-0)
• EPA Substance Registry System: 2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE(6852-58-0)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38-40-42/43
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 6852-58-0(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to yellow liquid

General Description

In vitro metabolism of N-benzyl-tert-butylamine in male hamster hepatic microsomal preparations has been studied. Kinetic studies of frustrated Lewis pair (FLP)-catalyzed hydrogenation and deuteration of N-benzylidene-tert-butylamine suggests that the reaction proceeds via autoinductive catalysis.

InChI:InChI=1/C11H15N/c1-11(2,3)12-9-10-7-5-4-6-8-10/h4-9H,1-3H3

Upstream product

• 3376-24-7 (Z)-N-benzylidene-2-methylpropan-2-amine oxide 
• 3378-72-1 N-tert-butylbenzylamine 
• 3585-81-7 2-tert-butyl-3-phenyloxaziridine 
• 100-68-5 methyl-phenyl-thioether 
• 5894-65-5 N-t-butylbenzamide 
• 100-52-7 benzaldehyde 
• 7515-80-2 N-isopropyl-N-tert-butylamine 
• 75-64-9 tert-butylamine 
• 103-49-1 dibenzylamine 
• 103-67-3 benzyl-methyl-amine 
• 620-40-6 tribenzylamine 
• 758640-21-0 N-Benzylaniline 
• 103-83-3 N,N'-dimethylbenzylamine 
• 780-25-6 N-benzylidene benzylamine 

Downstream Products

• 101775-07-9 tert-butyl-(1-phenyl-but-3-enyl)-amine 
• 66090-41-3 3,5-di-tert-butyl-2-(1-cyano-2,2-dimethyl-propylidene)-6-oxo-4-phenyl-[1,3]oxazinane-5-carbonitrile 
• 138877-81-3 2-(Methylthio)-4-phenyl-1-isopropyl-5-(isopropylamino)imidazole hydrochloride 
• 138877-74-4 3-tert-Butyl-1-isopropyl-5-isopropylamino-2-methylsulfanyl-4-phenyl-3H-imidazol-1-ium; chloride 
• 118825-52-8 tert-Butyl-(2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-1-phenyl-heptyl)-amine 
• 120347-68-4 2-(N-t-butyliminomethyl)-trans-cinnamonitrile 
• 120347-65-1 methyl 2-(N-t-butyliminomethyl)-trans-cinnamate 
• 52095-44-0 (E)-2-styrylbenzaldehyde 
• 120347-57-1 2-(N-t-butyliminomethyl)-trans-stilbene 
• 126415-71-2 methyl 2,2-dimethyl-3-phenyl-3-(N-tert-butylamino)propanoate 
• 104616-96-8 N-t-Butyl N-(1-phenyl-2,2-dimethylpropyl)-amine 
• 93598-59-5 3-tert-Butyl-2,6-diphenyl-2,3-dihydro-[1,3]oxazin-4-one 
• 93598-62-0 3-tert-Butyl-5,6-dimethyl-2-phenyl-2,3-dihydro-[1,3]oxazin-4-one 
• 87352-00-9 (Z)-3-chloro-3-cyano-N-tert-butyl-4-phenyl-2-azetidinone 

Relevant articles and documents

Supramolecular Engineering of Discrete Pt(II)?Pt(II) Interactions for Visible-Light Photocatalysis

Visible-light photosensitizers have emerged as a sustainable and environmentally friendly medium for organic transformation. Herein, we have developed a supramolecular strategy for manipulating visible-light photosensitization and photocatalytic efficienc

Remarkably Efficient Iridium Catalysts for Directed C(sp2)-H and C(sp3)-H Borylation of Diverse Classes of Substrates

Here we describe the discovery of a new class of C-H borylation catalysts and their use for regioselective C-H borylation of aromatic, heteroaromatic, and aliphatic systems. The new catalysts have Ir-C(thienyl) or Ir-C(furyl) anionic ligands instead of the diamine-type neutral chelating ligands used in the standard C-H borylation conditions. It is reported that the employment of these newly discovered catalysts show excellent reactivity and ortho-selectivity for diverse classes of aromatic substrates with high isolated yields. Moreover, the catalysts proved to be efficient for a wide number of aliphatic substrates for selective C(sp3)-H bond borylations. Heterocyclic molecules are selectively borylated using the inherently elevated reactivity of the C-H bonds. A number of late-stage C-H functionalization have been described using the same catalysts. Furthermore, we show that one of the catalysts could be used even in open air for the C(sp2)-H and C(sp3)-H borylations enabling the method more general. Preliminary mechanistic studies suggest that the active catalytic intermediate is the Ir(bis)boryl complex, and the attached ligand acts as bidentate ligand. Collectively, this study underlines the discovery of new class of C-H borylation catalysts that should find wide application in the context of C-H functionalization chemistry.

Chromium-Catalyzed Reductive Cleavage of Unactivated Aromatic and Benzylic C-O Bonds

Reductive cleavage of aromatic and benzylic C-O bonds by chromium catalysis is reported. This deoxygenative reaction was promoted by low-cost CrCl 2precatalyst combined with poly(methyl hydrogen siloxane) as the mild reducing agent, providing a strategy in forming reduced motifs by cleavage of unactivated C-O bonds. A range of functional groups such as bromide, chloride, fluoride, hydroxyl, amino, and alkoxycarbonyl can be retained in the reduction.