75486-40-7

Upstream product

• 42854-99-9 o-nitrobenzyl chloroformate 
• 75517-65-6 (5S,6R,7S)-7-(1-Hydroxy-ethyl)-2,2,5-trimethyl-3-oxa-1-aza-bicyclo[4.2.0]octan-8-one 
• 72808-94-7 1-acetoxy-2-methyl-buta-1,3-diene 
• 75486-38-3 4-(2-hydroxy-1-methyl-ethyl)-2-azetidinone 
• 75486-39-4 (6S)-2,2,5S-Trimethyl-3-oxa-1-azabicyclo[4.2.0] octan-8-one 
• 75521-16-3 (6S,5R)-1-aza-3-oxa-2,2,5-trimethylbicyclo<4.2.0>octan-8-one 

Relevant academic research and scientific papers

Synthetic carbapenem antibiotics II. Stereoisomers of 7-hydroxyethyl-2,2,5-trimethyl-3-oxa-1-azabicyclo[4.2.0]-octan-8-one

The titled compounds are key synthetic intermediates in the structure-activity relationship studies of novel 1-methyl carbapenem antibiotics. Preparation and structural determination of these stereoisomers by X-ray crystallography and proton NMR spectroscopy are reported.