754958-79-7

Basic information

• Product Name: (S)-3-Benzyloxy-2-(2-tert-butoxycarbonylamino-ethylamino)-propionic acid
• CAS NO: 754958-79-7
• Molecular Weight: 338.404
• Mol File: 754958-79-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-Benzyloxy-2-(2-tert-butoxycarbonylamino-ethylamino)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Benzyloxy-2-(2-tert-butoxycarbonylamino-ethylamino)-propionic acid(754958-79-7)
• EPA Substance Registry System: (S)-3-Benzyloxy-2-(2-tert-butoxycarbonylamino-ethylamino)-propionic acid(754958-79-7)

Safety Data

• Hazardous Substances Data: 754958-79-7(Hazardous Substances Data)

Upstream product

• 4726-96-9 O-Benzyl-L-serine 
• 89711-08-0 N-(t-butoxycarbonyl)glycinal 
• 4530-20-5 BOC-glycine 
• 121505-93-9 tert-butyl N-{[methoxy(methyl)carbamoyl]methyl}carbamate 

Downstream Products

• 1026448-72-5 (S)-3-Benzyloxy-2-[(2-tert-butoxycarbonylamino-ethyl)-trimethylsilanyl-amino]-propionic acid 

Relevant articles and documents

Building units for N-backbone cyclic peptides. Part 4. Synthesis of protected Nα-functionalized alkyl amino acids by reductive alkylation of natural amino acids

A new method for the synthesis of protected Nα-(ω-Y-alkyl) amino acids (Y is a thio, amino or carboxy group) and related compounds by reductive alkylation of natural amino acids is reported. These new amino acids serve as building units for the synthesis of backbone-cyclic peptides. They are orthogonally protected at the α-amino position by butoxycarbonyl (Boc) or 9-fluorenylmethoxycarbonyl (Fmoc), using trimethylsilyl temporary protection, to allow for their incorporation into peptides by solid phase peptide synthesis.