7550-18-7Relevant academic research and scientific papers
Copper activation of boronic acids: Factors affecting reactivity
Frauenlob, Robin,Garcia, Carlos,Butler, Susan,Bergin, Enda
, p. 432 - 435 (2014)
The generation of nucleophiles from the combination of aryl boronic acids and catalytic amounts of copper salt allows a reactivity distinct from other organometallic species, such as organolithiums or Grignard reagents. Here we examine how the electronic
A copper-catalyzed petasis reaction for the synthesis of tertiary amines and amino esters
Frauenlob, Robin,Garcia, Carlos,Bradshaw, Gary A.,Burke, Helen M.,Bergin, Enda
experimental part, p. 4445 - 4449 (2012/06/18)
We have developed a copper-catalyzed process for the coupling of aldehydes, amines, and boronic acids. This allows greater reactivity with simple aryl boronic acids and allows coupling reactions to proceed that previously failed. Initial mechanistic studi
