755029-51-7Relevant academic research and scientific papers
Silver-Catalyzed Efficient Synthesis of Oxindoles and Pyrroloindolines via α-Aminoalkylation of N-Arylacrylamides with Amino Acid Derivatives
Kanyiva, Kyalo Stephen,Makino, Sohei,Shibata, Takanori
, p. 496 - 499 (2018/03/06)
α-Aminoalkylation of N-arylacrylamides with amino acid derivatives was achieved by silver-catalysis in moderate to high yields. The reaction provides an efficient strategy for the synthesis of functionalized oxindoles, and is suitable for a wide range of N-arylacrylamides and amino acids, both of which are inexpensive and readily available. The oxindoles obtained were readily transformed into densely functionalized pyrroloindolines by deprotection and cyclization in one pot.
Synthesis and cytotoxic activity of novel hexahydropyrrolo[2,3-b]indole imidazolium salts
Zhou, Yunjing,Duan, Kunyun,Zhu, Liang,Liu, Zhengfeng,Zhang, Chaobo,Yang, Lijuan,Li, Minyan,Zhang, Hongbin,Yang, Xiaodong
, p. 460 - 465 (2016/01/09)
A series of novel hexahydropyrrolo[2,3-b]indole-1H-imidazolium salts were synthesized and evaluated in vitro against a panel of human tumor cell lines. The results suggest that the 5,6-dimethyl-benzimidazole ring, and substitution of the imidazolyl-3-posi
