75508-73-5Relevant academic research and scientific papers
Suzuki-Miyaura, α-ketone arylation and dehalogenation reactions catalyzed by a versatile N-heterocyclic carbene-palladacycle complex
Navarro, Oscar,Marion, Nicolas,Oonishi, Yoshihiro,Kelly III, Roy A.,Nolan, Steven P.
, p. 685 - 692 (2007/10/03)
The activity of the complex (IPr)PdCl(η2-N,C-C 12H7NMe2), 1 [IPr = (N,N′-bis(2,6- diisopropylphenyl)-imidazol)-2-ylidene], in the Suzuki-Miyaura cross-coupling reaction involving unactivated aryl chlorides and triflates with arylboronic acids at room temperature in technical grade 2-propanol is described. These conditions allow for the synthesis of di- and tri-ortho-substituted biaryls in very short reaction times. This complex also displays very high activity for α-ketone arylation and dehalogenation reactions of activated and unactivated aryl chlorides.
The first general palladium catalyst for the Suzuki-Miyaura and carbonyl enolate coupling of aryl arenesulfonates
Nguyen, Hanh Nho,Huang, Xiaohua,Buchwald, Stephen L.
, p. 11818 - 11819 (2007/10/03)
The first general method for the palladium-catalyzed Suzuki-Miyaura and carbonyl enolate coupling of unactivated aryl arenesulfonates was developed utilizing XPhos, 1, and Pd(OAc)2. This is of significant interest because aryl tosylates and aryl benzenesulfonates are more easily handled and considerably less expensive than aryl triflates. This catalyst system effects the coupling of a variety of aryl, heteroaryl, and extremely hindered arylboronic acids with different aryl tosylates, under mild conditions. The same catalyst was employed in the first carbonyl enolate coupling of aryl arensulfonates. Copyright
Well-defined, air-stable (NHC)Pd(Allyl)Cl (NHC = N-heterocyclic carbene) catalysts for the arylation of ketones
Viciu, Mihai S.,Germaneau, Romain F.,Nolan, Steven P.
, p. 4053 - 4055 (2007/10/03)
(formula presented) A number of palladium-N-heterocyclic carbene (NHC) complexes were found to be active catalysts for the arylation of ketones. A large number of substrates, both aryl halides and ketones, are compatible with the reaction conditions. The ketone arylation reactions are achieved with low catalyst loading in short reaction times using aryl chlorides and triflates as reactive partners.
Antifungal triazole ethanol derivatives
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, (2008/06/13)
Antifungal and plant growth regulatory compounds of the formula STR1 in which R1 is alkyl, cycloalkyl or optionally substituted phenyl, and R2 is optionally substituted phenyl or benzyl.
New Synthesis of Benzofurans by SRN1 Reaction of ortho-Iodoanisole
Beugelmans, Rene,Ginsburg, Helene
, p. 508 - 509 (2007/10/02)
Starting from ortho-iodoanisole, 2-substituted benzofurans are obtained in high yield via aromatic nucleophilic radical substitution (SRN1).
