75526-74-8Relevant articles and documents
Total synthesis of tryprostatins A and B
Yamakawa, Takayuki,Ideue, Eiji,Iwaki, Yuzo,Sato, Ayumu,Tokuyama, Hidetoshi,Shimokawa, Jun,Fukuyama, Tohru
, p. 6547 - 6560 (2011/09/20)
Three distinct synthetic routes to the 2-prenyl tryptophan core skeleton of tryprostatins and their total syntheses are described. The strategies include a traditional gramine-mediated coupling reaction, Fuerstner indole synthesis, and our radical-mediated indole synthesis from o-alkenylphenyl isocyanide. The establishment of reliable conditions for the radical-mediated construction of indoles via a low-temperature radical initiator V-70 (2,2′-azobis(4- methoxy-2,4-dimethylvaleronitrile)) led to the highly efficient syntheses of tryprostatins A and B.
Studies on the Syntheses of Heterocyclic Compounds. Part 876. The Chiral Total Synthesis of Brevianamide E and Deoxybrevianamide E
Kametani, Tetsuji,Kanaya, Naoaki,Ihara, Masataka
, p. 959 - 963 (2007/10/02)
The chiral total synthesis of brevianamide E (1) and deoxybrevianamide E (2) starting from L-proline is described.Condensation of 2-(1,1,dimethylallyl)-3-dimethylaminomethylindole (3) and (-)-methyl 1,4-dioxoperhydropyrrolopyrazine-3-carboxylate (7
