75527-41-2

Upstream product

• 1073-06-9 3-fluorobromobenzene 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 75527-39-8 1-benzyl-4-(3-fluorophenyl)-piperidin-4-ol 

Downstream Products

• 75527-53-6 1-methyl-3-hydroxymethyl-3-(m-fluorophenyl)pyrrolidine 
• 75527-49-0 1-ethoxycarbonyl-4-(m-fluorophenyl)-3,4-epoxypiperidine 
• 75527-51-4 1-ethoxycarbonyl-3-formyl-3-(m-fluorophenyl)pyrrolidine 
• 75527-62-7 [3-(3-Fluoro-phenyl)-1-methyl-pyrrolidin-3-yl]-acetyl chloride 
• 75527-60-5 [3-(3-Fluoro-phenyl)-1-methyl-pyrrolidin-3-yl]-acetic acid 
• 75527-58-1 1-methyl-3-cyanomethyl-3-(m-fluorophenyl)pyrrolidine 
• 75527-56-9 1-methyl-3-chloromethyl-3-(m-fluorophenyl)pyrrolidine 

Relevant academic research and scientific papers

Piperidine derivatives having renin inhibiting activity

Novel piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the novel piperidine derivatives of general formula I wherein R1, R2, R3, R4, Q, X, Z, m and n are as described herein.

Studies on Psychotropic Agents. VI. Synthesis of 1'-Methylspiro-3-one and Related Compounds

The title compounds (19) were synthesized by rearrangement of the 1-ethoxycarbonyl-4-aryl-3,4-epoxypiperidines (7) to give the 3-aryl-3-formylpyrrolidine derivatives (12) for pharmacological testing.Compound (19b) exhibited moderate central nervous system