7554-67-8Relevant academic research and scientific papers
Nitrogen-containing heterocycles from metal β-diketonates
Svistunova,Shapkin,Nikolaeva,Apanasenko
experimental part, p. 756 - 761 (2011/08/06)
Factors determining the reaction of metal β-diketonates with hydrazine, in particular the nature of central metal ion and structure of β-diketonate ligand, are discussed. The possibility for the preparation of other heterocyclic compounds via reaction of metal acetylacetonates with phenylhydrazine, o-phenylenediamine, urea, and thiourea was studied.
FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS
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Page/Page column 292, (2008/06/13)
A series of 6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-4(5H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
MIGRATION TENDENCIES OF FUNCTIONAL GROUPS TOWARD SIGMATROPIC REARRANGEMENT IN 3,3-DISUBSTITUTED 3H-PYRAZOLES
Schiess, Peter,Stalder, Henri
, p. 1417 - 1420 (2007/10/02)
3,3-Disubstituted 3H-pyrazoles la - e aromatise through an intramolecular sigmatropic 1,5-(1,2-)shift of one of the quaternary groups.From a kinetic study of the uncatalysed and of the acid catalysed isomerisation reaction migration tendencies of functional groups in sigmatropic rearrangement toward neutral and toward cationic centers are obtained.
