75567-38-3 Usage
Chemical compound
20-Deoxyingenol 3-angelate is a chemical compound that is derived from the sap of the Euphorbia peplus plant.
Cancer treatment potential
It has been investigated for its potential use in cancer treatment, particularly for the treatment of actinic keratosis, a precancerous skin condition.
Selective cancer cell killing
Studies have shown that 20-Deoxyingenol 3-angelate has the ability to selectively kill cancer cells while sparing healthy cells, making it a promising candidate for targeted cancer therapy.
Anti-inflammatory and immunomodulatory effects
It has been shown to have anti-inflammatory and immunomodulatory effects, which may further contribute to its potential as a cancer treatment.
Need for further research
Further research is needed to fully understand the potential benefits and risks of using 20-Deoxyingenol 3-angelate in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 75567-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,5,6 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 75567-38:
(7*7)+(6*5)+(5*5)+(4*6)+(3*7)+(2*3)+(1*8)=163
163 % 10 = 3
So 75567-38-3 is a valid CAS Registry Number.
75567-38-3Relevant articles and documents
Identification, structural modification, and dichotomous effects on human immunodeficiency virus type 1 (HIV-1) replication of ingenane esters from Euphorbia kansui
Liu, Qingbo,Li, Wei,Huang, Li,Asada, Yoshihisa,Morris-Natschke, Susan L.,Chen, Chin-Ho,Lee, Kuo-Hsiung,Koike, Kazuo
, p. 618 - 627 (2018)
Euphorbia kansui showed potent anti-HIV-1 activity during screening of a library composed of plant extracts from Euphorbiaceae and Thymelaeaceae families. Bioassay-guided isolation led to identification of ingenane esters as the active compounds. Further chemical modification resulted in 3-(2-naphthoyl)ingenol (23), which exhibited the most potent anti-HIV-1 activity. Compound 23 also acted as an HIV-1-latency-reversing agent on activation of HIV-1 replication in a latently infected U1 cell model and a T cell latent HIV-1 model JLat-A2.
