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Quinazoline, 8-methyl(7CI,8CI,9CI) is a bicyclic organic compound with the molecular formula C9H8N2, characterized by a benzene ring fused to a pyrimidine ring and featuring an 8-methyl substitution. This quinazoline derivative holds promise in the pharmaceutical industry due to its presence in biologically active molecules and potential therapeutic applications.

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  • 7557-03-1 Structure
  • Basic information

    1. Product Name: Quinazoline, 8-methyl- (7CI,8CI,9CI)
    2. Synonyms: Quinazoline, 8-methyl- (7CI,8CI,9CI);8-Methylquinazoline
    3. CAS NO:7557-03-1
    4. Molecular Formula: C9H8N2
    5. Molecular Weight: 144.17322
    6. EINECS: N/A
    7. Product Categories: PYRIMIDINE
    8. Mol File: 7557-03-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: Quinazoline, 8-methyl- (7CI,8CI,9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: Quinazoline, 8-methyl- (7CI,8CI,9CI)(7557-03-1)
    11. EPA Substance Registry System: Quinazoline, 8-methyl- (7CI,8CI,9CI)(7557-03-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 7557-03-1(Hazardous Substances Data)

7557-03-1 Usage

Uses

Used in Pharmaceutical Industry:
Quinazoline, 8-methyl(7CI,8CI,9CI) is utilized as a key structural component in the development of various pharmaceutical agents. Its applications span across multiple therapeutic areas, including:
1. Anticancer Agents:
Quinazoline, 8-methyl(7CI,8CI,9CI) serves as a crucial moiety in the design of anticancer drugs, targeting a range of cancer types. Its ability to interact with cellular targets and disrupt essential biological processes makes it a valuable component in the fight against cancer.
2. Antiviral Agents:
This quinazoline derivative is employed in the creation of antiviral medications, leveraging its potential to inhibit viral replication and reduce the severity of viral infections.
3. Antimalarial Agents:
Quinazoline, 8-methyl(7CI,8CI,9CI) is used in the development of antimalarial drugs, targeting the Plasmodium parasites responsible for malaria and offering a potential treatment for this widespread disease.
4. Central Nervous System Disorders:
Quinazoline, 8-methyl(7CI,8CI,9CI) also plays a role in the treatment of various central nervous system disorders, with its potential to modulate neurotransmission and alleviate symptoms associated with these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 7557-03-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,5 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7557-03:
(6*7)+(5*5)+(4*5)+(3*7)+(2*0)+(1*3)=111
111 % 10 = 1
So 7557-03-1 is a valid CAS Registry Number.

7557-03-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-Methylquinazoline

1.2 Other means of identification

Product number -
Other names 8-Methyl-chinazolin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7557-03-1 SDS

7557-03-1Relevant articles and documents

POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS

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Paragraph 00225, (2017/07/06)

The present invention relates to compounds of Formula (I) and pharmaceutically acceptable compositions thereof, useful as toll-like receptor 7/8 (TLR7/8) antagonists. In Formula (I), Ring A is aryl or heteroaryl; Ring B is aryl or heteroary; and X is C(R4)2, O, NR4, S, S(R4), or S(R4)2.

NOVEL HETEROCYCLIC CARBOXAMIDES AS MODULATORS OF KINASE ACTIVITY

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Page/Page column 29-30, (2013/07/05)

The invention provides novel heterocyclic carboxamide compounds compounds according to Formula (I) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.

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