7560-85-2

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 4-methylpiperazine-1-carboxylate is used as an intermediate in the synthesis of various drugs, including antipsychotics, antihistamines, and antiviral medications, for its ability to contribute to the development of effective therapeutic agents.
Used in Agrochemical Industry:
Methyl 4-methylpiperazine-1-carboxylate is used as a building block in the production of agrochemicals, contributing to the development of new molecules for agricultural applications and enhancing crop protection.
Used in Organic Chemistry:
Methyl 4-methylpiperazine-1-carboxylate is used as a versatile chemical in organic chemistry for its role in the synthesis of various organic compounds, expanding the scope of chemical research and development.

InChI:InChI=1/C7H14N2O2/c1-8-3-5-9(6-4-8)7(10)11-2/h3-6H2,1-2H3

Upstream product

• 50606-31-0 methyl piperazine-1-carboxylate 
• 109-01-3 1-methyl-piperazine 
• 79-22-1 methyl chloroformate 

Downstream Products

• 109648-85-3 1-dodecyl-4-methoxycarbonyl-1-methyl-piperazinium; bromide 
• 106-58-1 N,N'-dimethylpiperazine 

Relevant academic research and scientific papers

Polyethylene glycol-based homologated ligands for nicotinic acetylcholine receptors

A homologous series of polyethylene glycol (PEG) monomethyl ethers were conjugated with three ligand series for nicotinic acetylcholine receptors. Conjugates of acetylaminocholine, the cyclic analog 1-acetyl-4,4-dimethylpiperazinium, and pyridyl ether A-84543 were prepared. Each series was found to retain significant affinity at nicotinic receptors in rat cerebral cortex with tethers of up to six PEG units. Such compounds are hydrophilic ligands which may serve as models for fluorescent/affinity probes and multivalent ligands for nAChR.

RAPID REDUCTIVE-CARBOXYLATION OF SECONDARY AMINES. ONE POT SYNTHESIS OF TERTIARY N-METHYLATED AMINES

Various tertiary N-methylated amines were synthesized by using a new reductive-carboxylation approach.Secondary amines, on carboxylation with carbon dioxide under moderate reaction conditions, afforded their corresponding carbamate esters, which, on in situ lithium aluminum hydride reduction, gave desired tertiary N-methylated amines in high yield.