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Trinactin is a hydrophobic cyclic ester and a member of the macrotetrolide complex produced by a range of Streptomyces sp. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5, and interferon-γ.

7561-71-9

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7561-71-9 Usage

Uses

Used in Pharmaceutical Industry:
Trinactin is used as a macrotetrolide antibiotic for its ability to inhibit T-cell proliferation and cytokine production, making it a potential candidate for immunosuppressive applications.
Used in Research Applications:
Trinactin is used as a research tool for studying the mechanisms of T-cell proliferation and cytokine production, as well as for investigating the selectivity of monovalent cation ionophores for ammonium and potassium.

Check Digit Verification of cas no

The CAS Registry Mumber 7561-71-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,6 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7561-71:
(6*7)+(5*5)+(4*6)+(3*1)+(2*7)+(1*1)=109
109 % 10 = 9
So 7561-71-9 is a valid CAS Registry Number.
InChI:InChI=1/C43H70O12/c1-9-29-21-33-13-17-36(50-33)25(5)40(44)48-24(4)20-32-12-16-37(49-32)26(6)41(45)53-30(10-2)22-34-14-18-39(51-34)28(8)43(47)55-31(11-3)23-35-15-19-38(52-35)27(7)42(46)54-29/h24-39H,9-23H2,1-8H3/t24-,25-,26+,27+,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,38+,39-/m0/s1

7561-71-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Trinactin

1.2 Other means of identification

Product number -
Other names (1r,2r,5r,7r,10s,11s,14s,16s,19r,20r,23r,25r,28s,29s,32s,34s)-5,14,23-triethyl-2,11,20,29,32-pentamethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7561-71-9 SDS

7561-71-9Upstream product

7561-71-9Downstream Products

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