75619-94-2

Upstream product

• 151-50-8 potassium cyanide 
• 538-51-2 benzylidene phenylamine 
• 87751-45-9 1,2,5-Triphenyl-3-piperidin-1-ylmethyl-imidazolidin-4-one 
• 4553-59-7 2-anilino-2-phenylacetonitrile 
• 100-52-7 benzaldehyde 

Downstream Products

• 87751-51-7 1,2,5-Triphenyl-5-piperidin-1-ylmethyl-1,5-dihydro-imidazol-4-one 
• 75619-97-5 1,2,5-triphenyl-imidazolidin-4-one 
• 87751-58-4 2-Methyl-1,2,5-triphenyl-imidazolidin-4-one 
• 87751-57-3 1,2,2,5-Tetraphenyl-imidazolidin-4-one 
• 87751-52-8 5-Morpholin-4-ylmethyl-1,2,5-triphenyl-1,5-dihydro-imidazol-4-one 

Relevant academic research and scientific papers

Reactions of 4-Imidazolidinone and 4-Imidazolinone Derivatives

Treatment of 4-imidazolidinones (1) with dimethyl sulphate, acrylonitrile or acetic anhydride brings about N-alkylation or acylation to give 3.Hydrolysis of N-cyanoethyl derivatives (3f,g) affords the corresponding N-carboxyethyl derivatives (4a,b).Attempted cyclization of 4a with acetic anhydride gives 4-acetoxy-4-imidazolinone (6).Mannich reaction of 1 gives the N-Mannich bases (7).However, a similar reaction on 4 imidazolinones (2) affords the C-Mannich bases (8).The base 8a can be converted into S-(p-tolylthiomethyl) derivative (8h) by reaction with p-thiocre-sol.Reaction of Grignard reagents with 4-imidazolinones (2) affords 4-imidazolidinone derivatives (9).

Reinvestigation of the Behaviour of Benzal-anils towards the Action of Potassium Cyanide

Reinvestigation of the behaviour of benzal-anils (1) towards the action of potassium cyanide was found to give a mixture of 4-imidazolidinone (6) and 4-imidazolone (7). 6 was also obtained by benzaldehyde addition to α-arylamino-α-phenylacetonitrile (2) o