75624-75-8 Usage
Uses
Used in Organic Synthesis:
[(3-methylisoxazol-5-yl)methyl]triphenylphosphonium chloride is used as a reactant for the formation of carbon-carbon bonds through the Wittig reaction, a widely utilized method in organic chemistry for creating new carbon-carbon double bonds.
Used in Pharmaceutical Synthesis:
[(3-methylisoxazol-5-yl)methyl]triphenylphosphonium chloride serves as a precursor in the synthesis of various pharmaceuticals, contributing to the development of new medications and therapies.
Used in Agrochemical Synthesis:
[(3-methylisoxazol-5-yl)methyl]triphenylphosphonium chloride is also used as a starting material in the creation of agrochemicals, which are chemicals used in the agricultural industry to enhance crop protection and yield.
Used in Photodynamic Therapy for Cancer Treatment:
[(3-methylisoxazol-5-yl)methyl]triphenylphosphonium chloride has been studied for its potential use in photodynamic therapy, a treatment method that involves the use of a light-sensitive drug, light, and oxygen to kill cancer cells. Its role in this therapy could be significant, offering a novel approach to cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 75624-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,2 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 75624-75:
(7*7)+(6*5)+(5*6)+(4*2)+(3*4)+(2*7)+(1*5)=148
148 % 10 = 8
So 75624-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H21NOP.ClH/c1-19-17-20(25-24-19)18-26(21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23;/h2-17H,18H2,1H3;1H/q+1;/p-1
75624-75-8Relevant academic research and scientific papers
Reactions with Organophosphorus Compounds, XLVI. Reactivity Umpolung of 1,3-Dioxo Compounds through Introduction of a Triphenylphosphonio Group. - Regioselective Syntheses of Isoxazoles and Pyrazoles from (2,4-Dioxoalkyl)triphenylphosphonium Salts
Oehler, Elisabeth,Zbiral, Erich
, p. 2852 - 2867 (2007/10/02)
Phosphonium salts 2 and 6, upon deprotonation with BuLi and subsequent reaction with acyl halides, yield the γ-acyl derivatives 3 and 7, respectively, which on treatment with hydrochloric acid afford the corresponding (dioxoalkyl)phosphonium salts 4 and 8.Isoxazole derivatives 9 and 10 are formed regioselectivly from 4 and 8 with NH2OH*HCl, while with R-NH-NH2*HCl (R = H or C6H5) the pyrazole-containing phosphonium salts 14 and 15 are obtained in an analogous reaction.In each case the direction of cyclisation is different to the reactions of the corresponding non-phosphorus substituted 1,3-dioxo compounds.On treatment with aqueous NaOH 9 and 10 are cleaved to triphenylphosphane oxide and isoxazoles 11 and 12, while 14 and 15 yield the pyrazoles 16 and 17.Wittig reaction of 9a or 14a with aldehydes or ketones leads to the isoxazole olefins 13 or the pyrazole olefins 18, respectively.
