75638-35-6Relevant academic research and scientific papers
Sulfamic acid catalyzed direct condensation of aldehydes, amines, and TMSCN to α-aminonitriles at ambient temperature
Li, Zhenjiang,Sun, Yingjie,Ren, Xinghua,Wei, Ping,Shi, Yuhu,Ouyang, Pingkai
, p. 803 - 805 (2007)
A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide in the presence of a catalytic amount of sulfamic acid at room temperature. Georg Thieme Verlag Stuttgart.
[HP(HNCH2CH2)3N]NO3: An efficient homogeneous and solid-supported promoter for aza and thia-Michael reactions and for Strecker reactions
Fetterly, Brandon M.,Jana, Nirmal K.,Verkade, John G.
, p. 440 - 456 (2007/10/03)
In the presence of a catalytic amount of an azaphosphatrane nitrate salt, amines and thiols react readily with Michael acceptors. The salt is also an efficient promoter for the one pot synthesis of α-amino and α-amidonitriles. By anchoring the salt to Merrifield Resin, a reusable heterogeneous catalyst is obtained for these reactions. Evidence is presented for catalysis being attributable solely to the NO3- ion.
A Novel Synthesis of N-Substituted Amino Acids
Naim, S. Shawkat,Khan, Naseem H.,Siddiqui, Amin A.
, p. 622 - 624 (2007/10/02)
Addition of hydrocyanic acid to schiff bases has led to a method for the synthesis of N-substituted amino acid hydrochlorides in excellent yield (ca. 90percent).
