75644-23-4Relevant academic research and scientific papers
ACYLIERUNG VON HETEROCYCLEN MIT KOHLENSAEUREDERIVATEN-III; SYNTHESEN VON BENZIMIDAZOLO (1,2,4)THIADIAZOLINEN
Martin, D.,Tittelbach, F.
, p. 2311 - 2314 (2007/10/02)
The addition products of benzimidazolinethione and isocyanates are easily cyclized to benzimidazolo(1,2,4)thiadiazoline systems 4 by treatment with Br2/NEt3.The thio-analogues 9 were synthesized from 2-aminophenyl thioureas and thiophosgene followe
The Chemistry of o-Phenylene Di-isothiocyanate. Part 1. Some Reactions with N-Nucleophiles
Griffiths, David,Hull, Roy,Seden, Timothy P.
, p. 1240 - 1244 (2007/10/02)
Reactions of o-phenylene di-isothiocyanate are described with a variety of nitrogen nucleophiles.Primary and secondary amines and also substituted hydrazines give 1:1 reaction products, 1-substituted thiocarbamoyl benzimidazoline-2-thiones.Hydrazine gives a 2:1 reaction product, to be regarded as a hydrazine salt.The products from primary amines are relatively unstable, yielding isothiocyanates and benzimidazoline-2-thione.Some Schiff bases and derivatives of isoquinoline give rise to thiadiazinobenzimidazoles.
