75648-84-9

Upstream product

• 100-39-0 benzyl bromide 
• 127654-95-9 (1-benzyl-2,5-bis-ethoxycarbonylmethylene)pyrrolidine 

Downstream Products

• 1043427-48-0 (2R,5S)-3-[2-(2-benzyloxy-ethyl)-5-(2-hydroxy-ethyl)-pyrrolidin-1-yl]cyclohex-2-enone 
• 75648-85-0 3-[(2S,5R)-2-(2-Benzyloxy-ethyl)-5-(2-hydroxy-ethyl)-pyrrolidin-1-yl]-cyclohex-2-enone 

Relevant academic research and scientific papers

Formal total synthesis of (+)-gephyrotoxin

(Chemical Equation Presented) An efficient formal total synthesis of (+)-gephyrotoxin is described. The key step of our strategy relies on the diastereoselective reduction of a chiral pyrrolidine β-enamino ester obtained by condensation of (S)-phenylglycinol on a protected 8-hydroxy-3,6-dioxooctanoate.