75682-04-1Relevant academic research and scientific papers
Pinocembrin synthesis method
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Paragraph 0053; 0054; 0055; 0056, (2017/08/23)
The invention provides a pinocembrin synthesis method. The method comprises the following steps that under the room temperature condition, phloroglucinol and acetonitrile are stirred to be uniform, phosphorus oxychloride is added for a reaction, and 2,4,6-trihydroxyacetophenone is obtained; under the catalytic action of a catalyst L-proline, obtained 2,4,6-trihydroxyacetophenone and benzaldehyde are subjected to a ring closing reaction in DMF, and a crude pinocembrin product is obtained; the obtained crude pinocembrin product is subjected to recrystallization with ethyl alcohol, activated carbon is adopted for decolourization, and the pinocembrin is obtained. The synthesis method is simple in technology, low in cost, capable of saving time, high in yield and suitable for industrial production.
A simple synthesis of hydroxyisoflavanones
Gouda,Grover
, p. 142 - 144 (2007/10/03)
The isoflavanoids 7-hydroxyisoflavanone 4a, 7-hydroxy-3′, 4′-dimethoxyisoflavanone 4b, 5, 7-dihydroxy-3′, 4′-dimethoxyisoflavanone 4c, 5, 7-dihydroxy-2′-methoxyisoflavanone 4d, 5, 7-dihydroxy-3′, 4′-dimethoxyisoflavanone 4e and 5, 7-dihydroxy-4′-methoxyisoflavanone 4f have been conveniently prepared by using paraforomaldehyde and diethylamine as a base.
CATALYTIC TRANSFER HYDROGENATION, A CHEMO-SELECTIVE REDUCTION OF ISOFLAVONES TO ISOFLAVANONES
Krishnamurty, H.G.,Sathyanarayana, S.
, p. 1657 - 1664 (2007/10/02)
Isoflavones can be selectively reduced by catalytic transfer hydrogenation employing formic acid, ammonium formate or triethylammonium formate in the presence of 10percent Pd/C.The reaction is simple, clean and gives fair yields of isoflavanones.
A New General Synthesis of Hydroxy- and Methoxy-isoflavones
Jain, Amolak C.,Mehta, Anita
, p. 215 - 220 (2007/10/02)
A new general synthesis of hydroxy- (5e-h) and methoxy- (5e-d) isoflavones has been accomplished in overall yields of 47-73percent from the corresponding 2-hydroxydeoxybenzoins (1a-h).The first step involves reaction with appropriate amounts of ethoxymeth
A New General Synthesis of Polyhydroxyisoflavanones
Jain, Amolak C.,Sharma, Anita
, p. 338 - 339 (2007/10/02)
Hydroxyisoflavanones have been conveniently synthesised from hydroxydesoxybenzoins in 47-57 percent overall yields in four steps which could be carried out either continuously or by isolating the products at each stage.
Methylenation Studies of Desoxybenzoins : Characterisation of Minor Products and Debenzylation of Benzyloxyisoflavanones
Malik, M. L.,Grover, S. K.
, p. 208 - 211 (2007/10/02)
The minor products in the reaction of 2-hydroxy-4-benzyloxydesoxybenzoin and methylene iodide are found to be corresponding enol-methylene ethers and 3-iodomethyl isoflavanones as shown by spectral studies.The latter compounds also form from the correspon
