756822-47-6

Upstream product

• 5089-33-8 2-(4-bromophenyl)-1,1,1,3,3,3-hexamethyldisilazane 
• 7439-95-4 magnesium 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 905848-84-2 (4-aminophenyl)(1-aza-bicyclo[2,2,2]oct-4-yl)-methanone 
• 214360-73-3 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline 
• 1492833-65-4 (Z)-4-(4-aminophenyl)but-3-en-1-ol 

Relevant academic research and scientific papers

A synthetic amino acid frequency that alcohol ester

The invention relates to a method of synthesizing aminophenylboronic acid pinacol ester. The method includes subjecting bromoaniline having different substitute positions to silanization protection, reacting with magnesium metal or butyl lithium, and performing boronization/deprotection/esterification to obtain a product. Raw materials and agents, which are adopted in the method, are cheap and easily available. Reaction conditions are mild. Only simple treatment is needed after a reaction in each step is finished. The method is capable of continuous operation. The total yield is 40-55%. The purity of the product is high. The method is suitable for large-scale amplification production.

Anti-Hiv Quinuclidine Compounds

The invention provides a therapeutic method for preventing or treating a pathological condition or symptom in a mammal, such as a human, wherein the infectivity of a pathogen such as a retrovirus toward mammalian cells is implicated and inhibition of its