756843-43-3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 69240-56-8 4-(4-bromophenoxy)benzaldehyde 
• 756843-42-2 benzyl-[4-(4-bromo-phenoxy)-benzyl]-(2-methyl-3-nitro-phenyl)-amine 
• 756843-41-1 [4-(4-bromo-phenoxy)-benzyl]-(2-methyl-3-nitro-phenyl)-amine 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 448957-04-8 N-(3-{benzyl[4-(4-(2-carboxyethyl)phenoxy)benzyl]amino}-2-methylphenyl)methanesulfonamide 

Relevant academic research and scientific papers

Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator

Bile acid conjugates of a selective nonsteroidal glucocorticoid receptor modulator were prepared and evaluated. Potent GR binding conjugates that showed improved metabolic stability were discovered. However, cellular potency and pharmacokinetics were not substantially improved.