756875-65-7Relevant academic research and scientific papers
Palladium-catalyzed synthesis of N-aryl pyrrolidines from γ-(N-arylamino) alkenes: Evidence for chemoselective alkene insertion into Pd-N bonds
Ney, Joshua E.,Wolfe, John P.
, p. 3605 - 3608 (2007/10/03)
The formation of a C-C and a C-N bond in a reaction between γ-(N-arylamino) alkenes and aryl bromides results in the stereoselective synthesis of substituted pyrrolidine derivatives (see scheme). Preliminary studies suggest these reactions proceed by intramolecular alkene insertion into the Pd-N bond of intermediate [Pd(Ar)(amido)] complexes. dba = dibenzylideneacetone, dppb = 1,3-bis(diphenylphosphanyl) butane.
