7569-34-8

Basic information

• Product Name: 1-ethylsulfonyl-4-methyl-benzene
• Synonyms: 1-ethylsulfonyl-4-methyl-benzene;4-Methylphenylethyl sulfone;Ethyl p-tolyl sulfone;Ethyl(p-tolyl) sulfone;p-Tolylethyl sulfone
• CAS NO: 7569-34-8
• Molecular Formula: C₉H₁₂O₂S
• Molecular Weight: 184.26
• Mol File: 7569-34-8.mol
• Article Data: 44

Chemical Properties

• Boiling Point: 323.7°C at 760 mmHg
• Flash Point: 178.9°C
• Appearance: /
• Density: 1.123g/cm³
• Vapor Pressure: 0.000486mmHg at 25°C
• Refractive Index: 1.514
• CAS DataBase Reference: 1-ethylsulfonyl-4-methyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethylsulfonyl-4-methyl-benzene(7569-34-8)
• EPA Substance Registry System: 1-ethylsulfonyl-4-methyl-benzene(7569-34-8)

Safety Data

• Hazardous Substances Data: 7569-34-8(Hazardous Substances Data)

Usage

General Description

1-ethylsulfonyl-4-methyl-benzene, also known as ethyl p-tolyl sulfone, is a chemical compound with the molecular formula C9H12O2S. It is a colorless to pale yellow liquid that is used as an intermediate in the production of pharmaceuticals and agrochemicals. It is also used as a solvent and as a component in the production of dyes and pigments. Due to its sulfone group, it exhibits high thermal stability and chemical resistance, making it useful in various industrial applications. It is important to handle this chemical with caution, as it is irritant to the skin, eyes, and respiratory system, and may cause allergic reactions in some individuals.

InChI:InChI=1/C9H12O2S/c1-3-12(10,11)9-6-4-8(2)5-7-9/h4-7H,3H2,1-2H3

Upstream product

• 64-67-5 diethyl sulfate 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 622-63-9 ethyl p-tolyl sulfide 
• 75-03-6 ethyl iodide 
• 1829-92-1 triethylsulfonium iodide 
• 919466-30-1 2-(toluene-4-sulfonyl)-propionic acid 
• 106-45-6 para-thiocresol 
• 100-42-5 styrene 
• 31350-99-9 1-[(1-bromoethyl)sulfonyl]-4-methylbenzene 
• 5961-59-1 N-methyl-N-(4-methoxyphenyl)amine 
• 64-17-5 ethanol 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 624-31-7 4-tolyl iodide 
• 80-40-0 ethyl ester of p-toluenesulfonic acid 

Downstream Products

• 14799-11-2 1-phenyl-2-p-tosylpropan-1-ol 
• 103-19-5 di(p-tolyl) disulfide 
• 131947-30-3 2-phenyl-3-(4-tolylthio)imidazo<1,2-a>pyridine 

Relevant articles and documents

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.

Iodine-Mediated Sulfenylation of Imidazo[1,2- a ]pyridines with Ethyl Arylsulfinates

A simple iodine-mediated approach is reported for the synthesis of sulfenylated imidazo[1,2- a ]pyridines through the reaction of imidazo[1,2- a ]pyridines with ethyl arylsulfinates under mild conditions. The reaction scope was investigated, and a plausible mechanism is proposed to elucidate the reaction process and activation mode. The results indicate that ethyl sulfinates are efficient sulfur sources for the construction of C-S bonds.

A biradical oxo-molybdenum complex containing semiquinone and: o -aminophenol benzoxazole-based ligands

We report a new mononuclear molybdenum(iv) complex, MoOLBISLSQ, in which LSQ (2,4-di-tert-butyl o-semibenzoquinone ligand) has been prepared from the reaction of the o-iminosemibenzoquinone form of a tridentate non-innocent benzoxazole ligand, LBIS, and MoO2(acac)2. The complex was characterized by X-ray crystallography, elemental analysis, IR and UV-vis spectroscopy and magnetic susceptibility measurements. The crystal structure of MoOLBISLSQ revealed a distorted octahedral geometry around the metal centre, surrounded by one O and two N atoms of LBIS and two O atoms of LSQ. The effective magnetic moment (μeff) of MoOLBISLSQ decreased from 2.36 to 0.2 μB in the temperature range of 290 to 2 K, indicating a singlet ground state caused by antiferromagnetic coupling between the metal and ligand centred unpaired electrons. Also, the latter led to the EPR silence of the complex. Cyclic voltammetry (CV) studies indicate both ligand and metal-centered redox processes. MoOLBISLSQ was applied as a catalyst for the oxidative cleavage of cyclohexene to adipic acid and selective oxidation of sulfides to sulfones with aqueous hydrogen peroxide. This journal is