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(Chloromethyl)(triethyl)silane, with the chemical formula (Et3Si)CH2Cl, is an organosilicon compound characterized by its clear, colorless liquid appearance and a pungent odor. It is highly flammable and serves as a versatile reagent in organic synthesis, particularly as a silylating agent. (chloromethyl)(triethyl)silane is instrumental in the creation of pharmaceuticals, agrochemicals, functional materials, silicon-containing polymers, silicone resins, and coatings.

757-34-6

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757-34-6 Usage

Uses

Used in Pharmaceutical Synthesis:
(Chloromethyl)(triethyl)silane is used as a silylating agent for the synthesis of pharmaceuticals, facilitating the formation of specific molecular structures that are otherwise challenging to achieve. Its reactivity allows for the creation of new chemical bonds, enhancing the diversity of pharmaceutical compounds.
Used in Agrochemical Production:
In the agrochemical industry, (chloromethyl)(triethyl)silane is utilized as a reagent in the synthesis of various agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used in Functional Material Synthesis:
(Chloromethyl)(triethyl)silane is employed as a silylating agent in the production of functional materials, where its ability to form stable siloxane bonds is crucial for the creation of materials with specific properties, such as thermal stability and chemical resistance.
Used in Silicon-Containing Polymer Synthesis:
As a reagent, (chloromethyl)(triethyl)silane is used in the synthesis of silicon-containing polymers, which are known for their unique properties, such as high thermal stability and resistance to environmental degradation.
Used in Silicone Resin and Coating Production:
(Chloromethyl)(triethyl)silane serves as a precursor in the production of silicone resins and coatings, which are valued for their excellent weather resistance, flexibility, and durability in various applications, including automotive, construction, and consumer goods industries.
Due to its reactive nature, (chloromethyl)(triethyl)silane should be handled with caution, and it is essential to store it in a cool, well-ventilated area to ensure safety during its use in various industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 757-34-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,5 and 7 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 757-34:
(5*7)+(4*5)+(3*7)+(2*3)+(1*4)=86
86 % 10 = 6
So 757-34-6 is a valid CAS Registry Number.

757-34-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name chloromethyl(triethyl)silane

1.2 Other means of identification

Product number -
Other names triethylsilylmethyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:757-34-6 SDS

757-34-6Relevant academic research and scientific papers

Linear Hydroaminoalkylation Products from Alkyl-Substituted Alkenes

Warsitz, Michael,Doye, Sven

supporting information, p. 15121 - 15125 (2020/10/23)

The regioselective conversion of alkyl-substituted alkenes into linear hydroaminoalkylation products represents a strongly desirable synthetic transformation. In particular, such conversions of N-methylamine derivatives are of great scientific interest, because they would give direct access to important amines with unbranched alkyl chains. Herein, we present a new one-pot procedure that includes an initial alkene hydroaminoalkylation with an α-silylated amine substrate and a subsequent protodesilylation reaction that delivers linear hydroaminoalkylation products with high selectivity from simple alkyl-substituted alkenes. For that purpose, new titanium catalysts have been developed, which are able to activate the α-C?H bond of more challenging α-silylated amine substrates. In addition, a direct relationship between the ligand structure of the new catalysts and the obtained regioselectivity is described.

COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS

-

Paragraph 001071; 001073; 001074; 001075, (2019/01/10)

The present disclosure, among other things, provides technologies for synthesis, including reagents and methods for stereoselective synthesis. In some embodiments, the present disclosure provides compounds useful as chiral auxiliaries. In some embodiments, the present disclosure provides reagents and methods for oligonucleotide synthesis. In some embodiments, the present disclosure provides reagents and methods for chirally controlled preparation of oligonucleotides. In some embodiments, technologies of the present disclosure are particularly useful for constructing challenging internucleotidic linkages, providing high yields and stereoselectivity.

Design, synthesis, and evaluation of nonaqueous silylamines for efficient CO2 capture

Switzer, Jackson R.,Ethier, Amy L.,Hart, Emily C.,Flack, Kyle M.,Rumple, Amber C.,Donaldson, Jordan C.,Bembry, Ashley T.,Scott, Owen M.,Biddinger, Elizabeth J.,Talreja, Manish,Song, Myoung-Geun,Pollet, Pamela,Eckert, Charles A.,Liotta, Charles L.

, p. 299 - 307 (2014/03/21)

A series of silylated amines have been synthesized for use as reversible ionic liquids in the application of post-combustion carbon capture. We describe a molecular design process aimed at influencing industrially relevant carbon capture properties, such as viscosity, temperature of reversal, and enthalpy of regeneration, while maximizing the overall CO2-capture capacity. A strong structure-property relationship among the silylamines is demonstrated in which minor structural modifications lead to significant changes in the bulk properties of the reversible ionic liquid formed from reaction with CO 2.

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