757-34-6Relevant academic research and scientific papers
Linear Hydroaminoalkylation Products from Alkyl-Substituted Alkenes
Warsitz, Michael,Doye, Sven
supporting information, p. 15121 - 15125 (2020/10/23)
The regioselective conversion of alkyl-substituted alkenes into linear hydroaminoalkylation products represents a strongly desirable synthetic transformation. In particular, such conversions of N-methylamine derivatives are of great scientific interest, because they would give direct access to important amines with unbranched alkyl chains. Herein, we present a new one-pot procedure that includes an initial alkene hydroaminoalkylation with an α-silylated amine substrate and a subsequent protodesilylation reaction that delivers linear hydroaminoalkylation products with high selectivity from simple alkyl-substituted alkenes. For that purpose, new titanium catalysts have been developed, which are able to activate the α-C?H bond of more challenging α-silylated amine substrates. In addition, a direct relationship between the ligand structure of the new catalysts and the obtained regioselectivity is described.
COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS
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Paragraph 001071; 001073; 001074; 001075, (2019/01/10)
The present disclosure, among other things, provides technologies for synthesis, including reagents and methods for stereoselective synthesis. In some embodiments, the present disclosure provides compounds useful as chiral auxiliaries. In some embodiments, the present disclosure provides reagents and methods for oligonucleotide synthesis. In some embodiments, the present disclosure provides reagents and methods for chirally controlled preparation of oligonucleotides. In some embodiments, technologies of the present disclosure are particularly useful for constructing challenging internucleotidic linkages, providing high yields and stereoselectivity.
Design, synthesis, and evaluation of nonaqueous silylamines for efficient CO2 capture
Switzer, Jackson R.,Ethier, Amy L.,Hart, Emily C.,Flack, Kyle M.,Rumple, Amber C.,Donaldson, Jordan C.,Bembry, Ashley T.,Scott, Owen M.,Biddinger, Elizabeth J.,Talreja, Manish,Song, Myoung-Geun,Pollet, Pamela,Eckert, Charles A.,Liotta, Charles L.
, p. 299 - 307 (2014/03/21)
A series of silylated amines have been synthesized for use as reversible ionic liquids in the application of post-combustion carbon capture. We describe a molecular design process aimed at influencing industrially relevant carbon capture properties, such as viscosity, temperature of reversal, and enthalpy of regeneration, while maximizing the overall CO2-capture capacity. A strong structure-property relationship among the silylamines is demonstrated in which minor structural modifications lead to significant changes in the bulk properties of the reversible ionic liquid formed from reaction with CO 2.
