757-34-6

Basic information

• Product Name: (chloromethyl)(triethyl)silane
• CAS NO: 757-34-6
• Molecular Formula: C₇H₁₇ClSi
• Molecular Weight: 164.7484
• Mol File: 757-34-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 170.6°C at 760 mmHg
• Flash Point: 51.2°C
• Density: 0.861g/cm³
• Vapor Pressure: 1.94mmHg at 25°C
• Refractive Index: 1.416
• CAS DataBase Reference: (chloromethyl)(triethyl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: (chloromethyl)(triethyl)silane(757-34-6)
• EPA Substance Registry System: (chloromethyl)(triethyl)silane(757-34-6)

Safety Data

• Hazardous Substances Data: 757-34-6(Hazardous Substances Data)

Usage

General Description

(chloromethyl)(triethyl)silane is a chemical compound with the formula (Et3Si)CH2Cl. It is an organosilicon compound that is used as a reagent in organic synthesis and as a silylating agent. The compound is a clear, colorless liquid with a pungent odor and is highly flammable. It is primarily used as a silylating agent in the synthesis of pharmaceuticals, agrochemicals, and functional materials. It is also used as a reagent in the synthesis of silicon-containing polymers and as a precursor in the production of silicone resins and coatings. Due to its reactive nature, it should be handled with caution and stored in a cool, well-ventilated area.

Upstream product

• 617-86-7 triethylsilane 
• 3294-59-5 Phenyl-(dibromchlormethyl)-quecksilber 
• 186581-53-3 diazomethane 
• 994-30-9 triethylsilyl chloride 
• 74-97-5 chlorobromomethane 
• 1558-25-4 (chloromethyl)trichlorosilane 
• 2386-64-3 ethylmagnesium chloride 
• 33454-02-3 (chloromethyl)diethylchlorosilane 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 37628-29-8 (1-Phenyl-2-triethylsilanyl-ethyl)-phosphonic acid diethyl ester 
• 18441-99-1 triethylsilylmethanethiol 
• 140618-47-9 4,4',4-tris(triethylsilylmethyl)triphenylamine 
• 140618-52-6 4-triethylsilylmethyltriphenylamine 
• 125504-03-2 (triethylsilylmethyl)diphenylphosphate 
• 994-49-0 hexaethyl disiloxane 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS

The present disclosure, among other things, provides technologies for synthesis, including reagents and methods for stereoselective synthesis. In some embodiments, the present disclosure provides compounds useful as chiral auxiliaries. In some embodiments, the present disclosure provides reagents and methods for oligonucleotide synthesis. In some embodiments, the present disclosure provides reagents and methods for chirally controlled preparation of oligonucleotides. In some embodiments, technologies of the present disclosure are particularly useful for constructing challenging internucleotidic linkages, providing high yields and stereoselectivity.

SYNTHESIS OF SILICON-CONTAINING ESTERS OF PHOSPHORUS ACIDS AND STUDY OF THEIR THERMAL STABILITY. 3. THERMAL REARRANGEMENT OF TRIORGANOSILYLMETHYL ESTERS OF DIPHENYL PHOSPHORIC ACID

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