75702-97-5 Usage
Uses
Used in Pharmaceutical Industry:
Ethanone, 1-cyclopropyl-2,2,2-trifluoro(9CI) is used as a reagent for the synthesis of N-alkylphenylalaninamides from pyridinylphenyland oxobipyridinylamines. These compounds serve as human GPR 142 agonists, which have potential applications as anti-diabetic agents. Ethanone, 1-cyclopropyl-2,2,2-trifluoro(9CI) plays a crucial role in the development of new treatments for diabetes by modulating the activity of the GPR 142 receptor, which is involved in glucose homeostasis.
Used in Drug Development:
In the field of drug development, Ethanone, 1-cyclopropyl-2,2,2-trifluoro(9CI) is utilized as a key intermediate in the synthesis of various biologically active compounds. Its unique structure allows for the formation of diverse chemical entities with potential therapeutic applications. Ethanone, 1-cyclopropyl-2,2,2-trifluoro(9CI)'s reactivity and stability make it an attractive candidate for the development of new drugs targeting various diseases and conditions.
Used in Chemical Research:
Ethanone, 1-cyclopropyl-2,2,2-trifluoro(9CI) is also employed in chemical research as a model compound to study the effects of trifluoromethyl and cyclopropyl groups on the reactivity and properties of ketones. This research contributes to the understanding of structure-activity relationships in organic chemistry and can lead to the discovery of new synthetic methods and applications for related compounds.
Used in the Synthesis of Cytochrome P 450 Inhibitors:
Ethanone, 1-cyclopropyl-2,2,2-trifluoro(9CI) is used as a starting material in the preparation of cytochrome P 450 inhibitors. Cytochrome P 450 enzymes are involved in the metabolism of various drugs and xenobiotics, and their inhibition can be beneficial in certain therapeutic contexts. Ethanone, 1-cyclopropyl-2,2,2-trifluoro(9CI)'s unique structure allows for the development of selective inhibitors with potential applications in the treatment of drug resistance and drug-drug interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 75702-97-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,0 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 75702-97:
(7*7)+(6*5)+(5*7)+(4*0)+(3*2)+(2*9)+(1*7)=145
145 % 10 = 5
So 75702-97-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H6FN.ClH/c4-3-1-5-2-3;/h3,5H,1-2H2;1H
75702-97-5Relevant academic research and scientific papers
Trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation of trifluoromethyl ketones
Wang, Yi,Yuan, Yu,Xing, Chun-Hui,Lu, Long
supporting information, p. 1045 - 1048 (2015/02/19)
A trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation reaction of indoles with alkyl and aryl trifluoromethyl ketones has been developed. The trifluoromethyl-substituted bisindolylalkane derivatives were synthesized in moderate to excellent yields.
Trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation of trifluoromethyl ketones
Wang, Yi,Yuan,Xing, Chun-Hui,Lu, Long
supporting information, p. 1045 - 1048 (2014/02/14)
A trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation reaction of indoles with alkyl and aryl trifluoromethyl ketones has been developed. The trifluoromethyl-substituted bisindolylalkane derivatives were synthesized in moderate to excellent yields.
Structural effects on thermal rearrangement of fulleroids to methanofullerenes. The prominent role of cyclopropyl vs aryl substituent
Kitamura, Hiroshi,Oshima, Takumi
, p. 293 - 296 (2008/09/19)
(Chemical Equation Presented) The kinetics of the thermal rearrangement of a series of novel cyclopropyl-substituted [5,6] open fulleroids to the [6,6] closed methanofullerenes have been investigated in comparison with the aryl-substituted homologues. The
2-[Trifluoroethylamine]oxazolines
-
, (2008/06/13)
This invention relates to trifluorethylamines and to a process for producing the same. These trifluorethylamines are substituted on the nitrogen atom with a lower alkyl or a cyclo lower alkyl radical. They are endowed with interesting pharmacologi
