75702-97-5

Basic information

• Product Name: Ethanone, 1-cyclopropyl-2,2,2-trifluoro- (9CI)
• Synonyms: Ethanone, 1-cyclopropyl-2,2,2-trifluoro- (9CI)
• CAS NO: 75702-97-5
• Molecular Formula: C₅H₅F₃O
• Molecular Weight: 138.0878096
• Product Categories: ACETYLHALIDE
• Mol File: 75702-97-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 59.3°C at 760 mmHg
• Appearance: /
• Vapor Pressure: 202mmHg at 25°C
• CAS DataBase Reference: Ethanone, 1-cyclopropyl-2,2,2-trifluoro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-cyclopropyl-2,2,2-trifluoro- (9CI)(75702-97-5)
• EPA Substance Registry System: Ethanone, 1-cyclopropyl-2,2,2-trifluoro- (9CI)(75702-97-5)

Safety Data

• Hazardous Substances Data: 75702-97-5(Hazardous Substances Data)

Usage

Uses

Trifluoromethyl Cyclopropyl Ketone is a derivative of Cyclopropanecarboxaldehyde (C989650); a reagent used in the preparation of N-alkylphenylalaninamides from pyridinylphenyl- and oxobipyridinylamines as human GPR 142 agonists for potential use as anti-diabetic agents and the cytochrome P 450 inhibition.

InChI:InChI=1/C3H6FN.ClH/c4-3-1-5-2-3;/h3,5H,1-2H2;1H

Upstream product

• 121749-65-3 α-(trifluoroacetyl)-γ-butyrolactone hydrate 
• 60128-03-2 hexyl cyclopropane carboxylate 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 4333-56-6 cyclopropyl bromide 

Downstream Products

• 75703-02-5 4-Methyl-1,1,1-trifluor-pentan-2-on 
• 1005344-39-7 cyclopropyl trifluoromethyl ketone tosylhydrazone 

Relevant articles and documents

Trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation of trifluoromethyl ketones

A trifluoromethanesulfonic acid-catalyzed solvent-free bisindolylation reaction of indoles with alkyl and aryl trifluoromethyl ketones has been developed. The trifluoromethyl-substituted bisindolylalkane derivatives were synthesized in moderate to excellent yields.

Structural effects on thermal rearrangement of fulleroids to methanofullerenes. The prominent role of cyclopropyl vs aryl substituent

(Chemical Equation Presented) The kinetics of the thermal rearrangement of a series of novel cyclopropyl-substituted [5,6] open fulleroids to the [6,6] closed methanofullerenes have been investigated in comparison with the aryl-substituted homologues. The