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11-TRANS LEUKOTRIENE E4, also known as 11-trans LTE4, is a C-11 double bond isomer of Leukotriene E4 (LTE4). It is formed through the slow isomerization of the C-11 double bond of LTE4. Both LTE4 and 11-trans LTE4 exhibit equipotent activity in contracting guinea pig ileum, indicating their similar biological effects.

75715-88-7

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75715-88-7 Usage

Uses

Used in Pharmaceutical Research:
11-TRANS LEUKOTRIENE E4 is used as a research compound in the pharmaceutical industry for studying its biological effects and potential therapeutic applications. Its equipotent activity to LTE4 in contracting guinea pig ileum makes it a valuable tool for understanding the mechanisms of action and developing new drugs targeting leukotrienes.
Used in Biochemical Studies:
In the field of biochemistry, 11-TRANS LEUKOTRIENE E4 is utilized for investigating the role of leukotrienes in various physiological and pathological processes. This helps researchers gain insights into the molecular mechanisms underlying leukotriene-mediated responses and their implications in health and disease.
Used in Drug Development:
11-TRANS LEUKOTRIENE E4 serves as a lead compound in drug development, particularly for the treatment of conditions associated with leukotriene-mediated inflammation and immune responses. Its similar potency to LTE4 allows researchers to explore its potential as a therapeutic agent and develop novel drugs with improved efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 75715-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,1 and 5 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 75715-88:
(7*7)+(6*5)+(5*7)+(4*1)+(3*5)+(2*8)+(1*8)=157
157 % 10 = 7
So 75715-88-7 is a valid CAS Registry Number.

75715-88-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 11-trans Leukotriene E4

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75715-88-7 SDS

75715-88-7Downstream Products

75715-88-7Relevant academic research and scientific papers

SYNTHESIS OF LEUKOTRIENES - NEW SYNTHESIS OF NATURAL LEUKOTRIENE A4

Rokach, Joshua,Young, Robert N.,Kakushima, Masatoshi,Lau, Cheuk-Kun,Seguin, Rick,at al.

, p. 979 - 982 (2007/10/02)

The acetonides of D- or L-glyceraldehyde are chiral synthons for an efficient and versatile synthesis of the natural leukotrienes A4, C4, D4 and E4 and equally can be used to prepare the corresponding unnatural analogues.

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