75716-46-0Relevant academic research and scientific papers
N- versus O-arylation of aminoalcohols: Orthogonal selectivity in copper-based catalysts
Shafir, Alexandr,Lichtor, Phillip A.,Buchwald, Stephen L.
, p. 3490 - 3491 (2008/01/01)
Two complementary protocols for copper-catalyzed arylation of aminoalcohols were developed. Selective N-arylation was accomplished at room temperature using 2-isobutyrylcyclohexanone (a β-diketone) as supporting ligand, while selective O-arylation require
Imidazole compounds
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, (2008/06/13)
A novel class of imidazo heterocyclic compounds, pharmaceutical compositions comprising them and use thereof in the treatment and/or prevention of diseases and disorders related to the histamine H3 receptor. More particularly, the compounds are useful for the treatment and/or prevention of diseases and disorders in which an interaction with the histamine H3 receptor is beneficial.
New, Easily Removable Poly(ethylene glycol) Supports for the Liquid-Phase Method of Peptide Synthesis
Pillai, V. N. Rajasekharan,Mutter, Manfred,Bayer, Ernst,Gatfield, Ian
, p. 5364 - 5370 (2007/10/02)
Poly(ethylene glycol) (PEG) was derivatized with a number of acid-cleavable and photocleavable anchoring groups in order to test the applicability of these derivatives as supports in liquid-phase peptide synthesis.PEG was subjected to rapid and quantitati
