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Usage

Uses

Used in Pharmaceutical Industry:
2,4-dichloro-1-ethynylbenzene is used as an intermediate for the production of pharmaceuticals. It plays a crucial role in the synthesis of various medicinal compounds, contributing to the development of new drugs and therapies.
Used in Pesticide Industry:
In the pesticide industry, 2,4-dichloro-1-ethynylbenzene is employed as an intermediate in the manufacturing process of certain pesticides. Its chemical properties make it suitable for the creation of effective and targeted pest control agents.
Used in Dye Synthesis:
2,4-dichloro-1-ethynylbenzene is used as a starting material in the synthesis of dyes. Its unique structure allows for the development of a wide range of colorants used in various applications, including textiles, plastics, and printing inks.
Used in Plasticizer Production:
2,4-dichloro-1-ethynylbenzene is also utilized in the production of plasticizers, which are additives used to increase the flexibility and workability of plastics. 2,4-dichloro-1-ethynylbenzene contributes to the creation of various plasticizer types, enhancing the performance of plastic materials in different industries.
Safety Precautions:
It is essential to handle 2,4-dichloro-1-ethynylbenzene with care, as it can be harmful if it comes into contact with the skin or if it is inhaled. Proper safety measures, such as wearing protective gear and ensuring proper ventilation, should be taken during its use and storage.

Upstream product

• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 1201-99-6 trans-2,4-dichlorocinnamic acid 
• 212138-65-3 2,4-dichloro-1-(2,2-dibromovinyl)benzene 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 
• 89-75-8 2,4-dichlorobenzoyl chloride 
• 113639-19-3 1-(2,4-Dichloro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone 
• 50-84-0 2,4 dichlorobenzoic acid 
• 120-83-2 2,4-dichlorophenol 
• 41605-69-0 2,4-dichlorophenyl trifluoromethanesulfonate 
• 113655-34-8 1,3,3-trimethyl-2-(α-chloro-2,4-dichlorostyryl)indolenium chloride 

Downstream Products

• 1291079-91-8 N-(2-(3-(2,4-dichlorophenyl)-1-hydroxy-1-phenylprop-2-ynyl)phenyl)-4-methylbenzenesulfonamide 
• 63111-80-8 2-(2,4-dichlorophenyl)-imidazo[1,2-a]pyridine 
• 1572959-51-3 1-(2-((2,4-dichlorophenyl)ethynyl)phenyl)ethanone 

Relevant academic research and scientific papers

1,2,3-triazole compounds with antitumor activity and preparation method for 1,2,3-triazole compounds

The present invention relates to three 1,2,3-triazole compounds with aryl structures on the left sides, and the general structural formulae thereof are as shown in the specification. The three compounds have good antitumor activity.

Convenient synthesis of terminal alkynes from anti-3-aryl-2,3- dibromopropanoic acids using a K2CO3/DMSO system

A convenient, efficient, and generally applicable method was developed for the synthesis of terminal alkynes from anti-3-aryl-2,3-dibromopropanoic acids in the presence of DMSO and K2CO3.

Cs2CO3-mediated synthesis of terminal alkynes from 1,1-dibromo-1-alkenes

An unprecedented route to prepare terminal alkynes from 1,1-dibromo-1-alkenes mediated by Cs2CO3 was proven. 1,1-Dibromo-1-alkenes bearing various functional groups were efficiently converted to corresponding terminal alkynes in moderate to excellent yields.

Novel 3-phenylprop-2-ynylamines as inhibitors of mammalian squalene epoxidase.

The synthesis of a novel series of 3-phenylprop-2-ynylamines as selective mammalian squalene epoxidase inhibitors is described. Structure activity relationship studies led to the discovery of compound 19, 1-[3-(3,5-dichlorophenyl)-prop-2-ynyl]-3- methylpiperidine hydrochloride with an IC50 of 2.8 +/- 0.6 microM against rat liver squalene epoxidase. Against 23 strains of fungal squalene epoxidase compound 19 was found to be inactive.

CRF receptor antagonists and methods relating thereto

CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, such as stroke.

ACETYLENIC FRAGMENTATION OF ACYL DERIVATIVES OF THE FISCHER BASE

Indolenium salts, which readily undergo cleavage in aqueous alkali to give a monosubstituted acetylene and 1,3,3-trimethyl-2-oxindole, are formed when acyl derivatives of the Fischer base are heated with phosphorus oxychloride.Various aryl- and hetarylacetylenes can be conveniently obtained by this method.

An approach to the synthesis of unsymmetrically substituted chlorobiphenyls

The Diels-Alder cycloaddition of o-chloranil with phenylacetylenes substituted with chlorine in the ring can afford chlorobiphenyls upon photodecomposition of the brodged diketone adduct.Biphenyls derived from 3-chloro-, 4-chloro-, 2,4-dichloro-, and (2,5