757189-92-7

Upstream product

• 1067-74-9 Methyl diethylphosphonoacetate 
• 625123-49-1 (2S)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-oxopyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 625123-46-8 methyl (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-(t-butyldimethylsilyl)-oxypyrrolidine-2-carboxylate 
• 625123-47-9 (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-(t-butyldimethylsilyl)-oxypyrrolidine-2-carboxaldehyde 
• 625123-48-0 (2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-hydroxypyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 382137-65-7 methyl-(2S,4R)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-hydroxypyrrolidine-2-carboxylate 
• 64154-78-5 4-benzyloxy-5-methoxy-2-nitrobenzoyl chloride 
• 60547-92-4 4-(benzyloxy)-5-methoxy-2-nitrobenzoic acid 

Downstream Products

• 757190-11-7 7-methoxy-8-{2-[(2S)-N-(4-benzyloxy-5-methoxy-2-aminobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-ethyl]oxy}-(11aS)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]-benzodiazepin-5,11-dione 
• 757190-12-8 7-methoxy-8-{3-[(2S)-N-(4-benzyloxy-5-methoxy-2-aminobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-propyl]oxy}-(11aS)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]-benzodiazepin-5,11-dione 
• 757190-09-3 methyl (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxylate 
• 757190-10-6 methyl (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxylate 
• 757189-99-4 (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-aminobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-aminobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757189-95-0 (2S)-N-{4-[(2S)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-ethyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757190-00-4 (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-aminobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-aminobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757189-96-1 (2S)-N-{4-[(2S)-N-(4-benzyloxy-5-methoxy-2-nitrobenzoyl)-pyrrolidine-2-carboxaldehyde diethyl thioacetal-4-(carboxamidomethylidene)-N-propyl]oxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 757190-15-1 (2S)-N-[4-benzyloxy-5-methoxy-2-nitrobenzoyl]-4-(carboxymethylidene)-pyrrolidine-2-carboxaldehyde diethyl thioacetal 

Relevant academic research and scientific papers

Synthesis and DNA binding affinity of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.

The synthesis of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers is reported and these dimers show significant DNA binding affinity and they also exhibit moderate anticancer activity.

Synthesis of novel C2 and C2-C8 linked pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide hybrids as DNA-binding agents

Synthesis of C2 and C2-C8 linked pyrrolobenzodiazepine-naphthalimide hybrids have been prepared that exhibit significant DNA-binding affinity and cytotoxicity.