757244-53-4

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 757244-51-2 [(1R,2S)-2-(4-Methoxy-benzyloxy)-1-(4-methoxy-phenoxymethyl)-3-oxo-propyl]-carbamic acid tert-butyl ester 
• 544455-38-1 ethyl (2E)-4-(4-methoxyphenoxy)but-2-enoate 
• 544455-39-2 (2S,3R)-3-Acetylamino-2-hydroxy-4-(4-methoxy-phenoxy)-butyric acid ethyl ester 
• 787632-48-8 (2S,3R)-3-Acetylamino-2-(4-methoxy-benzyloxy)-4-(4-methoxy-phenoxy)-butyric acid ethyl ester 
• 757244-50-1 (2S,3R)-3-tert-Butoxycarbonylamino-2-(4-methoxy-benzyloxy)-4-(4-methoxy-phenoxy)-butyric acid ethyl ester 

Downstream Products

• 757244-61-4 (2R,3R,4S,5R)-3-Hydroxy-2-hydroxymethyl-4-(4-methoxy-benzyloxy)-5-(4-methoxy-phenoxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 757244-58-9 [(1R,2S,3S)-3-Hydroxy-2-(4-methoxy-benzyloxy)-1-(4-methoxy-phenoxymethyl)-3-(R)-oxiranyl-propyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Stereodivergent total asymmetric synthesis of polyhydroxylated pyrrolidines via tandem allylic epoxidation and intramolecular cyclization reactions

Epoxidation of the allylic alcohols 10 and 11 using the VO(acac) 2/t-BuOOH system followed by an intramolecular 5-exo cyclization of the resulting δ-epoxycarbamates 12, 13, 18, and 19 has been shown to provide a general and efficient solution f