75755-52-1

Basic information

• Product Name: trans-ethyl 3-(4-chlorophenyl)oxirane-2-carboxylate
• Synonyms: trans-ethyl 3-(4-chlorophenyl)oxirane-2-carboxylate
• CAS NO: 75755-52-1
• Molecular Weight: 226.66
• Mol File: 75755-52-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: trans-ethyl 3-(4-chlorophenyl)oxirane-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: trans-ethyl 3-(4-chlorophenyl)oxirane-2-carboxylate(75755-52-1)
• EPA Substance Registry System: trans-ethyl 3-(4-chlorophenyl)oxirane-2-carboxylate(75755-52-1)

Safety Data

• Hazardous Substances Data: 75755-52-1(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 105-39-5 chloroacetic acid ethyl ester 
• 21911-74-0 (methyl-phenyl-amino)-acetic acid ethyl ester 
• 6048-06-2 ethyl-p-chlorocinnamate 
• 105-36-2 ethyl bromoacetate 
• 118171-52-1 ethyl 2-chloro-3-(4-chlorophenyl)-3-hydroxypropionate 
• 25709-55-1 1-<(ethoxycarbonyl)methyl>tetrahydrothiophenium bromide 
• 24393-52-0 ethyl (E)-3-(4-chlorophenyl)prop-2-enoate 
• 74087-85-7 3,3-dimethyldioxirane 

Downstream Products

• 1629011-21-7 (Z)-6-bromo-2-(4-chlorobenzylidene)-2H-imidazo[1,2-a]pyridin-3-one 
• 1629011-19-3 (Z)-2-(4-chlorobenzylidene)-6-methyl-2H-imidazo[1,2-a]pyridin-3-one 
• 30252-93-8 3-(2-amino-4-chloro-phenylsulfanyl)-3-(4-chloro-phenyl)-2-hydroxy-propionic acid 
• 69768-90-7 7-chloro-2-(4-chloro-phenyl)-3-hydroxy-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 
• 83769-36-2 3-(4-Chloro-phenyl)-3-fluoro-2-oxo-propionic acid ethyl ester 
• 30193-54-5 3-(2-Amino-4-chloro-phenylsulfanyl)-3-(4-chloro-phenyl)-2-hydroxy-propionic acid ethyl ester 
• 79963-76-1 3-(4-Chloro-phenyl)-3-fluoro-2-hydroxy-propionic acid ethyl ester 
• 27068-90-2 2-(4-chloro-phenyl)-3-hydroxy-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 
• 98995-10-9 2-amino-3-(4-chloro-phenyl)-3-hydroxy-propionic acid amide 
• 85174-84-1 trans-4-(4-Chlorphenyl)-2-oxooxazolidin-5-carbonsaeure-ethylester 
• 85174-84-1 cis-4-(4-Chlorphenyl)-2-oxooxazolidin-5-carbonsaeure-ethylester 
• 85174-82-9 trans-5-(4-Chlorphenyl)-2-oxooxazolidin-4-carbonsaeure-ethylester 
• 85174-82-9 cis-5-(4-Chlorphenyl)-2-oxooxazolidin-4-carbonsaeure-ethylester 

Relevant articles and documents

Facile construction of three-membered rings via benzyne-promoted Darzens-type reaction of tertiary amines

A range of tertiary amines having electron-withdrawing groups were activated in situ by benzyne, generated from 2-(trimethylsilyl)phenyl triflate and a fluoride source, and participated in the Darzens-type reaction with carbonyl compounds, imines, and vinyl ketones to afford structurally diverse epoxides, aziridines, and cyclopropanes, respectively, in moderate to excellent yields with high trans-selectivity. The reaction involves in situ formation of unstrained ammonium ylides from tertiary amines and benzyne, proceeds in the absence of transition metals and strong bases, and tolerates a wide variety of functional groups.

Epoxide Synthesis in Interfacial Solid-Liquid Conditions

In this paper an analysis of the factors responsible for discrimination among differing structures of organic reagents by the microcrystalline structure of solids is presented.As a vehicle of this study, the epoxide synthesis using three sulfur ylide precursors (sulfonium and sulfoxonium salts) and four microcrystalline solids was investigated.Neither the surface area nor the number of active sites at the solid surface control the epoxide yield.It appears that the cell lattice of the solid determines the ylide structure, its nucleophilicity, and thus the reaction yield.

Catalyst and method for isomerization

A catalyst for isomerization consisting essentially of a salt or complex salt represented by the formula: where M is a metal of Group IB, IIA, IIB or VIII of the periodic table, L is a ligand, Y is a conjugated base of a Bronsted acid, m is 0, 1, 2, 3 or 4 and n is 1, 2 or 3.