75767-99-6

Upstream product

• 43016-14-4 4-chloro-2'-hydroxychalcone dibromide 
• 873-73-4 4-n-chlorophenylacetylene 
• 1761-61-1 5-bromosalicyclaldehyde 
• 1450-75-5 5-Bromo-2-hydroxyacetophenone 
• 104-88-1 4-chlorobenzaldehyde 
• 73110-47-1 (E)-1-(5-Bromo-2-hydroxy-phenyl)-3-(4-chloro-phenyl)-propenone 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 920286-85-7 2-(4-chlorophenyl)-6-hexylamino-chromen-4-one 

Relevant academic research and scientific papers

Synthesis and biological activities of some flavones

Chalcones are synthesized by a base catalyzed Claisen Schmidt condensation reaction and then treated with dimethylsulphoxide in presence of iodine to get flavones. The synthesized compounds were evaluated for their antibacterial activity against Escherichia coilt P. aeruginosa, S. epidermidis and B. subtilis. All the flavones showed moderate to good activity. The structures of these compounds were confirmed by IR, UV, 1H NMR, Mass and elemental analysis.

Synthesis and biological activities of some flavones

Chalcones are synthesized by a base catalyzed Claisen Schmidt condensation reaction and then treated with dimethylsulphoxide in presence of iodine to get flavones. The synthesized compounds were evaluated for their antibacterial activity against Escherichia coli, P. aeruginosa, S. epidermidis and B. subtilis. All the flavones showed moderate to good activity. The structures of these compounds were confirmed by IR, UV, 1H NMR, Mass and elemental analysis.

A novel one pot route to flavones under dual catalysis, an organo- and a Lewis acid catalyst

Substituted phenylacetylenes react with various o-hydroxy aromatic aldehydes under dual catalysis of piperidine and FeCl3 in refluxing toluene to yield flavones in good to excellent yield. Atmospheric oxygen acts as stoichiometric oxidant in the process. Some of these compounds had been recently reported to show fair insecticidal activity against Spodoptera frugiperda.

Microwave enhanced palladium catalysed coupling reactions: A diversity-oriented synthesis approach to functionalised flavones

Microwave enhanced diversity-oriented synthesis (MEDOS) using palladium catalysed protocols is introduced as a powerful new strategy for the synthesis of systematically modified small molecules and is highlighted by application to functionalised flavones. The Royal Society of Chemistry 2006.