75792-34-6

Usage

InChI:InChI=1/C10H12O3/c1-3-13-9-6-4-5-8(7-11)10(9)12-2/h4-7H,3H2,1-2H3

Upstream product

• 492-88-6 3-ethoxysalicylaldehyde 
• 77-78-1 dimethyl sulfate 
• 75-03-6 ethyl iodide 
• 74-88-4 methyl iodide 

Downstream Products

• 108540-35-8 1-ethoxy-2-methoxy-3-(2-nitro-cis-propenyl)-benzene 
• 20999-17-1 (3-ethoxy-2-methoxy)-benzyl alcohol 
• 4767-71-9 3-ethoxy-2-methoxy-benzoic acid 
• 492-88-6 3-ethoxysalicylaldehyde 
• 408531-28-2 (3-ethoxy-2-methoxy-phenyl)-acetaldehyde-oxime 
• 1351593-05-9 (E)-1,1-diethoxy-N-(3-ethoxy-2-methoxybenzylidene)methanamine 
• 1361992-89-3 1,1-diethoxy-N-(3-ethoxy-2-methoxybenzyl)methanamine 
• 1351593-07-1 7-ethoxy-4-(4-ethoxy-3,5-dimethoxy-benzyl)-8-methoxy-isoquinoline 
• 1351593-09-3 (4-ethoxy-3,5-dimethoxyphenyl)-(7-ethoxy-8-methoxyisoquinolin-4-yl)-methanone 
• 1429254-01-2 C₂₅H₂₇N₃O₄ 
• 1178762-48-5 2-(3-ethoxy-2-methoxy-phenyl)ethylamine 
• 91134-28-0 (E)-3-ethoxy-2-methoxy-β-nitro-styrene 
• 95821-33-3 1-(2-Methoxy-3-ethoxy-phenyl)-2-hydroxy-3-benzyliden-cyclohexan-1-propionitril 
• 92652-91-0 4-Nitro-5-(2-methoxy-3-ethoxy-phenyl)-cyclohexen-⁽¹⁾ 

Relevant academic research and scientific papers

SAR based design of nicotinamides as a novel class of androgen receptor antagonists for prostate cancer

Molecular knowledge of pure antagonism and systematic SAR study offered a direction for structural optimization of DIMN to provide nicotinamides as a novel series of AR antagonists. Nicotinamides with extended linear scaffold bearing sterically bulky alkoxy groups on isoquinoline end were synthesized for H12 displacement. AR binding affinity and molecular basis of antiandrogenic effect establish the optimized derivatives, 7au and 7bb, as promising candidates of second generation AR antagonists for advanced prostate cancer.

SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS

The present invention relates generally to substituted isoquinolines and their use as tubulin polymerization inhibitors. In particular, the invention relates to substituted isoquinolines which possess useful therapeutic activity, use of these compounds in methods of therapy and the manufacture of medicaments as well as compositions containing these compounds

RECEPTOR FUNCTION REGULATING AGENT

An agent for regulating 14273 receptor function, which is useful as a preventing or treating drug for diabetes mellitus, hyperlipidemia or the like, is provided. An agent for regulating 14273 receptor function comprising a compound containing an aromatic ring and a group capable of releasing a cation.