757925-96-5

Upstream product

• 2905-24-0 3-Bromobenzenesulfonyl chloride 
• 108-00-9 N,N-dimethylethylenediamine 

Downstream Products

• 910903-40-1 N-(2-dimethylamino-ethyl)-3-(5-nitro-pyrimidin-2-ylamino)-benzenesulfonamide 
• 1356996-11-6 N-[2-(dimethylamino)ethyl]-3-({1-methyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}ethynyl)benzenesulfonamide 

Relevant academic research and scientific papers

ETHINYL-PYRAZOLE DERIVATIVE

Provided is a novel compound represented by formula [I] or a pharmaceutically acceptable salt thereof having antagonistic activity against group II metabolism-type glutamic acid (m-Glu) receptors. The compound or pharmaceutically acceptable salt thereof i

KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME

The present teachings provide a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. Also described are a pharmaceutical composition and method of use thereof.

FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE

The invention relates to compounds of formula (I) for the regulation of phosphoinositides 3-kinases activity and related diseases.

FUSED BICYCLIC COMPOUNDS AND USE THEREOF AS PI3K INHIBITORS

The invention relates to compounds of formula (I), for the regulation of phosphoinositides 3-kinases activity and related diseases.

Acetylenyl-pyrazolo-pyrimidine derivatives

The present invention relates to compounds of formula (I): wherein R1 to R3, A, M, L, E, G, and J are as defined in the description and claims. The invention also relates to a process for the manufacture of such compounds, pharmaceutical compositions containing them, and methods for treating CNS disorders.

Benzotriazine inhibitors of kinases

The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.