757966-64-6 Usage
Uses
Used in Pharmaceutical Industry:
1H,2H,3H,4H,5H-Pyrido[2,3-b][1,4]diazepin-2-one is used as a therapeutic agent for its potential anti-inflammatory properties, offering a new avenue for the treatment of inflammatory conditions by modulating the underlying biological processes.
Used in Oncology:
In the field of oncology, 1H,2H,3H,4H,5H-Pyrido[2,3-b][1,4]diazepin-2-one is utilized as an anti-cancer agent, targeting various types of cancer cells and potentially leading to the development of novel cancer therapies. Its specific mechanisms of action and interactions with cellular targets are under investigation to enhance its efficacy and selectivity.
Used in Neuropharmacology:
1H,2H,3H,4H,5H-Pyrido[2,3-b][1,4]diazepin-2-one also has potential applications in neuropharmacology, where it may contribute to the development of treatments for neurological disorders. Its effects on the nervous system and potential neuroprotective properties are areas of active research.
Used in Drug Development:
As a scaffold for drug development, 1H,2H,3H,4H,5H-Pyrido[2,3-b][1,4]diazepin-2-one provides a foundation for the design and synthesis of new pharmaceutical compounds. Its unique structure allows for modifications and optimizations that can lead to improved drug candidates with enhanced therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 757966-64-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,7,9,6 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 757966-64:
(8*7)+(7*5)+(6*7)+(5*9)+(4*6)+(3*6)+(2*6)+(1*4)=236
236 % 10 = 6
So 757966-64-6 is a valid CAS Registry Number.
757966-64-6Relevant academic research and scientific papers
Clozapine derived 2,3-dihydro-1H-1,4- and 1,5-benzodiazepines with D4 receptor selectivity: Synthesis and biological testing
Hussenether, Thomas,Huebner, Harald,Gmeiner, Peter,Troschuetz, Reinhard
, p. 2625 - 2637 (2007/10/03)
Novel 4-arylpiperazin-1-yl-substituted 2,3-dihydro-1H-1,4- and 1H-1,5-benzodiazepines and their aza-analogues were synthesized as debenzoclozapine derivatives for evaluation as potential D4-ligands. While Ki values of some of the title compounds came within the range of clozapine, they showed an impressively greater selectivity over other dopamine receptor subtypes, especially D2. For the most promising compounds, intrinsic activity and binding properties to serotonin 5-HT1A and 5-HT2 were also determined.
