757995-80-5Relevant articles and documents
A series of F-Element chelators; diaza crown ethers functionalized with catecholate binding substituents
Stein, Benjamin W.,Cary, Samantha K.,Berg, John M.,Birnbaum, Eva R.,Kozimor, Stosh A.,Mocko, Veronika,Scott, Brian L.
, p. 170 - 179 (2018)
Reported here is the preparation of azacrown ethers functionalized with catechol groups. The synthetic approach was (1st) novel in that it made use of the Mannich reaction and (2nd) valuable in that it provided an improved synthesis (in terms of practical
Bi-Aromatic And Tri-Aromatic Compounds As NADPH Oxidase 2 (Nox2) Inhibitors
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Paragraph 0156; 0157-0158, (2015/02/25)
Bi- and tri-aromatic compounds of the formula (I) wherein R1 to RIO and X are as defined, are Nox2 inhibitors that are useful as medicaments for the treatment of a disease or condition selected from: cardiovascular diseases, respiratory diseases, inflamma