758-24-7

Basic information

• Product Name: 1-BROMO-1-CHLORODIFLUOROETHYLENE
• Synonyms: 1-Bromo-1-chlorodifluoroethylene 97%;1-Bromo-1-chlorodifluoroethylene97%;1,1-difluoro-2-bromo-2-chloroethylene;2-BROMO-2-CHLORO-1,1-DIFLUOROETHYLENE;ETHYLENE,1-BROMO-1-CHLORO-2,2-DIFLUORO-;1-BROM0-2,2-DIFLUOROETHENE;1-BROMO-2,2-DIFLUOROETHENE;2-BROMO-2-CHLORO-1,1-DIFLUOROETHENE
• CAS NO: 758-24-7
• Molecular Formula: C₂BrClF₂
• Molecular Weight: 177.38
• EINECS: 212-062-8
• Mol File: 758-24-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 40-42
• Appearance: /
• Density: 1.888
• Refractive Index: 1.3846 (estimate)
• CAS DataBase Reference: 1-BROMO-1-CHLORODIFLUOROETHYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-1-CHLORODIFLUOROETHYLENE(758-24-7)
• EPA Substance Registry System: 1-BROMO-1-CHLORODIFLUOROETHYLENE(758-24-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 758-24-7(Hazardous Substances Data)

Usage

General Description

1-Bromo-1-chlorodifluoroethylene, also known as halon 1211, is a chemical compound used as a fire extinguishing agent. It is a colorless, volatile liquid with a slightly sweet odor and is highly reactive. It is listed as a class 1 ozone-depleting substance and is known to have negative effects on the environment. 1-Bromo-1-chlorodifluoroethylene is also a powerful greenhouse gas and has been regulated under the Montreal Protocol. Due to its significant ozone-depleting potential and adverse effects on the environment, the use of 1-Bromo-1-chlorodifluoroethylene has been restricted and phased out in many countries.

InChI:InChI=1/C2BrClF2/c3-1(4)2(5)6

Upstream product

• 354-51-8 1,2-dibromo-1-chloro-1,2,2-trifluoroethane 
• 22861-94-5 phenyl(1-bromo-1-chloro-2,2,2-trifluoroethyl)mercury 
• 421-36-3 2-Chloro-1,2-dibromo-1,1-difluoroethane 
• 151-67-7 1,1,1-trifluoro-2-bromo-2-chloroethane 
• 75-62-7 Bromotrichloromethane 
• 359-10-4 1-Chloro-2,2-difluoroethene 

Downstream Products

• 421-36-3 2-Chloro-1,2-dibromo-1,1-difluoroethane 
• 57596-70-0 N-acetyl-S-(2-bromo-2-chloro-1,1-difluoroethyl)-L-cysteine 
• 679-89-0 1-methoxy-1,1-difluoro-2-chloro-2-bromoethane 

Relevant articles and documents

Green synthesis method of ethyl bromodifluoroacetate

The invention provides a green synthesis method of ethyl bromodifluoroacetate. According to the method, 1,1-difluoro-1,2-dichloroethane is used as a starting material; elimination reaction is performed to obtain 1,1-difluoro-2-chloroethylene; the 1,1-difluoro-2-chloroethylene and bromine are subjected to addition to obtain 1,1-difluoro-1,2-dibromo-2-chloroethane; then, the elimination reaction is performed to obtain a 1,1-difluoro-2-bromine-2-chloroethylene; then, the 1,1-difluoro-2-bromine-2-chloroethylene and the bromine are subjected to addition to obtain 1,1-difluoro-1,2,2-tribromo-2-chloroethane; then, sulfur trioxide is used for oxidizing the 1,1-difluoro-1,2,2-tribromo-2-chloroethane; 1,1-difluoro-1-bromoacetyl chloride is obtained; finally, the 1,1-difluoro-1-bromoacetyl chloride and ethyl alcohol are esterified to obtain 2,2-difluoro-2-ethyl bromoacetate. The synthesis method has the advantages that the problems of recovery and utilization of waste materials of 1,1-difluoro-1,2-dichloroethane (R132b) are solved; no organic solvents are used in the reaction process; the oxidation step uses SO3 for oxidation; high temperature and high pressure or concentrated sulfuric acid is not needed; the safety is enhanced; the discharging of waste acid is reduced; the green production requirement is met; the product yield is relatively high; the green synthesis method is suitable for industrial production.

Practical preparation of potentially anesthetic fluorinated ethyl methyl ethers by means of bromine trifluoride and other methods

Synthetic methods, especially those that use bromine trifluoride as a fluorinating agent, are described for the preparation of a number of fluorinated ethyl methyl ethers in good yield and high purity. In all cases, medium-scale syntheses (8-22g) of potentially anesthetic compounds have been accomplished. The compounds are of sufficient purity (>99%) for biological evaluation.