75810-52-5Relevant academic research and scientific papers
LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO
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Page/Page column 75-76, (2010/02/11)
Compounds which function as melanocortin receptor ligands and having utility in the treatment of melanocortin receptor-based disorders. The compounds have the following structure (I): (R4)s (R 2)n N~ X1-X2 (CR1aCRlb)q 1~ N R1-lm 1 O R3 (I) including stereoisomers, prodrugs, and pharmaceutically acceptable salts thereof, wherein m, n, q, s, R1, R1a, R1b, R2, R3, R4, X1 X2 and X3 are as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.
Piperidine and pyrrolidine alcohols
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, (2008/06/13)
This disclosure describes novel compounds of the formula: STR1 where A is --CH2 OH or STR2 wherein R4 and R5 each independently represent hydrogen or lower alkyl having 1 to 2 carbon atoms or together with N represent STR3 and, R1 is hydrogen or lower alkyl having 1 to 2 carbon atoms, and R2 and R3 each independently represent hydrogen, chloro, fluoro, methyl, methoxy or together, represent methylenedioxy, and n is 1 or 2, provided that one of R2 and R3 is other than hydrogen which are useful as hypolipidemic agents.
