75815-10-0

Basic information

• Product Name: 4-methyl-5-(4-nitrophenyl)-1H-Imidazole
• Synonyms: 4-methyl-5-(4-nitrophenyl)-1H-Imidazole
• CAS NO: 75815-10-0
• Molecular Formula: C10H9N3O2
• Molecular Weight: 203.2
• Mol File: 75815-10-0.mol

Chemical Properties

• CAS DataBase Reference: 4-methyl-5-(4-nitrophenyl)-1H-Imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-5-(4-nitrophenyl)-1H-Imidazole(75815-10-0)
• EPA Substance Registry System: 4-methyl-5-(4-nitrophenyl)-1H-Imidazole(75815-10-0)

Safety Data

• Hazardous Substances Data: 75815-10-0(Hazardous Substances Data)

Upstream product

• 826-83-5 4(5)-phenyl-5(4)-methylimidazole 
• 75815-09-7 5-methyl-4-phenylimidazole nitrate 

Downstream Products

• 75814-85-6 N-cyano-S-methyl-N'-<4-(5-methyl-4-imidazolyl)phenyl>isothiourea 
• 75814-86-7 N-cyano-N'-methyl-N''-[4-(5-methyl-4-imidazolyl)phenyl]guanidine 
• 75815-15-5 5-methyl-4-(4-aminophenyl)imidazole 

Relevant articles and documents

Substituted indolines which inhibit receptor tyrosine kinases

Indolinones of the formula having an inhibitory effect on receptor tyrosine kinases and cyclin/CDK complexes, as well as on the proliferation of endothelial cells and various tumor cells. Exemplary are: (a) 3-Z-[1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-ethoxycarbonyl-2-indolinone, (b) 3-Z-[(1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-carbamoyl-2-indolinone, and (c) 3-Z-[1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-metboxycarbonyl-2-indolinone.

Conformational requirements for histamine H2-receptor inhibitors: A structure-activity study of phenylene analogues related to cimetidine and tiotidine

Two series of compounds related to cimetidine and tiotidine were synthesized as part of a study to evaluate the importance of conformational parameters in binding at histamine H2 receptors. The flexible methylthioethyl connecting chain was repl