826-83-5

Usage

Functional Groups

Imidazole and Phenyl

Type of Compound

Heterocyclic Aromatic Compound

Biological Activities

Anti-fungal and Anti-bacterial Properties

Applications

Building Block in Synthesis of Pharmaceutical Drugs and Agrochemicals

Use as a Ligand

Coordination Chemistry

Production

Dyes

Versatility

Wide Range of Applications in Pharmaceutical, Agricultural, and Chemical Industries

Upstream product

• 50-00-0 formaldehyd 
• 19347-08-1 acetic acid 1-methyl-2-oxo-2-phenyl-ethyl ester 
• 93-55-0 1-phenyl-propan-1-one 
• 83505-81-1 1-cyano-5-methyl-4-phenylimidazole 
• 77287-34-4 formamide 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 81225-10-7 6-Chloro-2-methyl-3-phenylpyrazine 
• 83505-93-5 2-azido-6-methyl-5-phenylpyrazine 
• 822-36-6 4-methyl-1H-imidazole 
• 98-80-6 phenylboronic acid 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 3473-63-0 formamidine acetic acid 
• 22596-45-8 2-methyl-2-nitro-3-phenyloxirane 
• 463-52-5 formamidine 

Downstream Products

• 117044-29-8 4-cyclohexyl-5-methyl-1⁽³⁾H-imidazole 
• 62576-11-8 1,4-dimethyl-5-phenyl-1H-imidazole 
• 1026004-93-2 3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propionaldehyde diethyl acetal 
• 148726-36-7 3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene 
• 75815-10-0 5-methyl-4-(4-nitrophenyl)imidazole 
• 141816-06-0 5-methyl-4-phenyl-1-(3-propylthio)imidazole 
• 149156-09-2 N-<2-amino>-6-(dimethylamino)phenyl>-N'-pentylurea 
• 141816-09-3 3-(dimethylamino)-2-nitro-N-benzyl-N-<3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propyl>aniline 
• 141816-08-2 3-chloro-2-nitro-N-benzyl-N-<3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propyl>aniline 
• 149156-08-1 2-amino>>-6-(dimethylamino)aniline 
• 1027509-93-8 3-chloro-2-nitro-N-formyl-N-<3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propyl>aniline 

Relevant academic research and scientific papers

6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepines derivatives as histamine H4 receptor ligands

The present patent application concerns new ligands of the H4-receptor, their process of preparation and their therapeutic use.

Highly efficient and eco-friendly protocol to functionalized imidazoles via ring-opening of α-nitro epoxides

A simple and direct synthesis of functionalized imidazoles from α-nitro-epoxides and amidines was developed. This reaction could proceed smoothly in a highly efficient and eco-friendly manner in moderate to excellent yields. A plausible mechanism has also

IDO inhibitors

Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R1, R4, and R5 are defined herein. Such compounds and compositions are useful for mod

Synthesis of 5-arylhistidines via a Suzuki-Miyaura cross-coupling

Microwave irradiation efficiently promoted the Suzuki-Miyaura reaction of a 5-bromohistidine with various arylboronic acids in the presence of a palladium catalyst. This methodology allowed the synthesis of histidines substituted at position 5 of the imid

Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives: new classes of dopamine receptor subtype specific ligands

Disclosed are compounds of the formula: wherein R1 represents optionally substituted aryl, heteroaryl, arylalkyl, or cycloalkyl groups; X, Z, and Y are optionally substituted nitrogen or carbon atoms; R3 and R4 are organic or inorganic substitutents which may togther form ring structutes; m is zero, one or two; and R5 and R6 are are organic or inorganic substituents; and the pharmaceutically acceptable addition salts thereof, which compounds are highly selective partial agonists or antagonists at brain dopamine receptor subtypes or prodrugs thereof and are useful in the diagnosis and treatment of affective disorders such as schizophrenia and depression as well as certain movement disorders such as Parkinsonism.

Synthesis of Some Alkyl- and Arylimidazoles

The pyrolysis of 2-azidopyrazines led to give 1-cyanoimidazoles, which were hydrolyzed in alkaline and acidic media to the corresponding imidazoles.This ring transformation occured also by photolysis.