75828-75-0Relevant articles and documents
Photolabile Protecting Group-Mediated Synthesis of 2-Deoxy-Glycosides
Li, Xiaoqian,Ma, Zhi,Liu, Rongkun,Hurevich, Mattan,Yang, You
supporting information, p. 3309 - 3314 (2021/10/14)
A green and efficient photolabile protecting group (PPG)-mediated glycosidation approach for the synthesis of 2-deoxy-glycosides is reported. By employing ortho-nitrobenzyl carbonate (oNBC) as PPG, N,N-dimethylformamide (DMF)-modulated SPhosAuNTf2/s
Design and synthesis of functionalized trisaccharides as p53-peptide mimics
Sakurai, Kaori,Kahne, Daniel
scheme or table, p. 3724 - 3727 (2010/08/22)
Oligosaccharides represent potentially useful scaffolds for the development of peptidomimetics. We report here the design and synthesis of functionalized trisaccharides modeled after an α-helical 15-mer peptide region of p53 which binds to its cellular regulator MDM2. The trisaccharide scaffold was obtained efficiently by applying the sulfoxide glycosylation reaction as a key methodology.
Efficient Route to 2-Deoxy β-O-Aryl-D-Glycosides via Direct Displacement of Glycosyl Iodides
Lam, Son N.,Gervay-Hague, Jacquelyn
, p. 4219 - 4222 (2007/10/03)
(Equation presented) The conversion of glycals to 2-deoxy glycosyl acetates followed by reaction with trimethylsilyl iodide affords the corresponding glycosyl iodides, which readily undergo substitution with aryl alkoxy anions to provide 2-deoxy-β-O-aryl