7583-74-6

Usage

General Description

1-Tert-Butyl-7-Oxa-Bicyclo[4.1.0]Heptane, also known as 1-tert-butyl-7-methyloxan, is a chemical compound with a bicyclic structure. It is a volatile and flammable liquid that is used in the synthesis of pharmaceuticals, fragrances, and fine chemicals. It is also used as a solvent and as a reagent in organic chemistry reactions. The compound is known for its unique structure and is used in various industrial processes. It is important to handle this chemical with caution due to its flammability and volatility.

Upstream product

• 3419-66-7 1-tert-butyl-1-cyclohexene 
• 75-91-2 tert.-butylhydroperoxide 

Downstream Products

• 87830-78-2 6,7-dimethyl-6-octenal dimethyl acetal 
• 99646-05-6 1-t-butylcyclopentane-1-carboxaldehyde 
• 99646-04-5 3-methoxy-2-t-butylcyclohexene 
• 99646-07-8 c-2-isopropenyl-2-methylcyclohexan-r-1-ol 
• 99646-03-4 t-2-methoxy-1-t-butylcyclohexan-r-1-ol 
• 98355-47-6 2-tert-butyl-trans-2-methoxycyclohexanol 
• 99646-06-7 2-methyl-c-2-(1-methyl-1-methoxyethyl)cyclohexan-r-1-ol 
• 77931-76-1 2-tert-butylcyclohex-2-en-1-ol 
• 1728-46-7 2-tert-butylcyclohexanone 
• 99646-06-7 2-methyl-t-2-(1-methoxy-1-methylethyl)cyclohexan-r-1-ol 
• 99646-12-5 2-(1-methoxy-1-methylethyl)-2-methylcyclohexanone 
• 99646-10-3 2-methoxy-2-t-butylcyclohexanone 
• 99646-08-9 t-2-(1-hydroxy-1-methylethyl)-2-methylcyclohexan-r-1-ol 
• 99646-08-9 c-2-(1-hydroxy-1-methylethyl)-2-methylcyclohexan-r-1-ol 

Relevant academic research and scientific papers

Highly efficient catalysts for epoxidation mediated by iminium salts

A range of substituted dihydroisoquinolinium salts has been tested in the catalytic epoxidation of several alkenes. Catalyst loadings as low as 0.5 mol% have been used in the epoxidation of 1-phenylcyclohexene. Georg Thieme Verlag Stuttgart.

Diverse pathways for the palladium(II)-mediated oxidation of olefins by tert-butylhydroperoxide

(Matrix presented) New procedures are described for the palladium-catalyzed oxidation of olefins by tert-butylhydroperoxide under slightly basic conditions in CH2Cl2 solution at 0-25°C.

Fluorinated alcohols: Effective solvents for uncatalysed epoxidations with aqueous hydrogen peroxide

Buffered aqueous hydrogen peroxide in combination with fluorinated alcohols (trifluoroethanol at reflux temperature or hexafluoro-2-propanol at room temperature) oxidises a variety of alkenes to the corresponding epoxides in high rates and fairly high yields, without the need for any catalyst.

Molybdenum-catalyzed epoxidations of oct-1-ene and cyclohexene with organic hydroperoxides: Steric effects of the alkyl substituents of the hydroperoxide on the reaction rate

A kinetic study of the epoxidation of oct-1-ene and cyclohexene with alkyl hydroperoxides is reported. The alkyl hydroperoxides were obtained in a moderate to high purity from the corresponding alcohols by acid-catalyzed exchange with hydrogen peroxide. The reaction rates in pseudo first-order experiments of these olefins with various alkyl hydroperoxides strongly depend on the structure of the alkyl group of the alkyl hydroperoxide. When one of the methyl groups in tert-butyl hydroperoxide (TBHP, 4a) is substituted by an alkyl group, R, the reaction rate decreases in the order Et > Pr > Bu > t BuCH2 > tBu. Substitution of two methyl groups of TBHP as in 1-ethyl-1-methylpropyl hydroperoxide (5a) and 1-ethyl-1-methylbutyl hydroperoxide (5b) showed a further decrease in reaction rate of epoxidation. When all three methyl groups are substituted by, for example, three ethyl groups as in 1,1-diethylpropyl hydroperoxide (6a) a decrease of approximately 99% in reaction rate is observed. Introduction of a ring system in the hydroperoxide such as in cyclohexyl hydroperoxide (3), 1-methyl-cyclohexyl hydroperoxide (2) and pinane hydroperoxide (1) also showed a dramatic decrease in reaction rate of epoxidation. An investigation of relative rates of epoxidation in competition experiments of cyclohexene and hex-1-ene with 1-tert-butylcyclohexene with different alkyl hydroperoxides also showed them to depend on the structure of the alkyl group of the alkyl hydroperoxide. These results are rationalized on the basis of a mechanism involving nucleophilic attack of the olefin on an alkylperoxomolybdenum(VI) intermediate. Bulky substituents at the α-position in the alkyl hydroperoxide can seriously impede the approach of the olefin to the O-O bond.