75849-14-8

Basic information

• Product Name: 3,4'-dihydroxy-αβ-dihydrochalcone
• Synonyms: 3,4'-dihydroxy-αβ-dihydrochalcone
• CAS NO: 75849-14-8
• Molecular Weight: 242.274
• Mol File: 75849-14-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,4'-dihydroxy-αβ-dihydrochalcone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4'-dihydroxy-αβ-dihydrochalcone(75849-14-8)
• EPA Substance Registry System: 3,4'-dihydroxy-αβ-dihydrochalcone(75849-14-8)

Safety Data

• Hazardous Substances Data: 75849-14-8(Hazardous Substances Data)

Upstream product

• 99-93-4 4-Hydroxyacetophenone 
• 100-83-4 meta-hydroxybenzaldehyde 
• 3654-50-0 3-(3-hydroxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one 

Downstream Products

• 73087-59-9 1-(4-hydroxyphenyl)-3-(3-hydroxyphenyl)propan-1-ol 

Relevant articles and documents

Intramolecular Alkylation of Phenols. Part 5. A Regiospecific Anionic Ring Closure of Phenols via Quinone Methides

The bis-magnesium salts of the triols (6a) and (6h) cyclise when heated in benzene with high ortho-regiospecificity to the corresponding bis-phenols (7) and (8).The triols (6k) and (6o) under the same conditions cyclise with high para-regiospecificity to the corresponding bis-phenols (7) and (8).Both (6a) and (6h) cyclise via o-quinone methides, and (6k) and (6o) via p-quinone methides.Results from the use of, inter alia, 18-crown-6, indicate that the high ortho-regiospecificity of the cyclisation of (6a) and (6h) is due to intramolecular Mg(II) bridging of the intermediate o-quinone methides.The high para-regiospecificity of cyclisation of (6k) and (6o) is due to steric hindrance towards o-cyclisation of the intermediate p-quinone methides presented by the Mg(II) cation.The unexpected facility with which (6a) and (6k) undergo ring closure is discussed.